A Comparison of Dysautonomias Comorbid with Cyclic Vomiting Syndrome and with Migraine
Cyclic vomiting syndrome (CVS) shares many features with migraine headache, including auras, photophobia, and antimigrainous treatment response being traditionally viewed as a migraine variant. Aims. To determine whether CVS is associated with the same disorders as migraine headache, and compare the...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2009-01-01
|
| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2009/701019 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832553395817283584 |
|---|---|
| author | Gisela Chelimsky Shruti Madan Amer Alshekhlee Elizabeth Heller Kevin McNeeley Thomas Chelimsky |
| author_facet | Gisela Chelimsky Shruti Madan Amer Alshekhlee Elizabeth Heller Kevin McNeeley Thomas Chelimsky |
| author_sort | Gisela Chelimsky |
| collection | DOAJ |
| description | Cyclic vomiting syndrome (CVS) shares many features with migraine headache, including auras, photophobia, and antimigrainous treatment response being traditionally viewed as a migraine variant. Aims. To determine whether CVS is associated with the same disorders as migraine headache, and compare these associations to those in healthy control subjects. Methods. Cross-sectional study of patients utilizing the ODYSA instrument, evaluating the probability of 12 functional/autonomic diagnoses, CVS, migraine, orthostatic intolerance (OI), reflex syncope, interstitial cystitis, Raynaud's syndrome, complex regional pain syndrome (CRPS), irritable bowel syndrome, functional dyspepsia, functional abdominal pain, fibromyalgia, and chronic fatigue syndrome. Control subjects were age-matched gender-matched friends. Patients had to fulfill criteria for CVS or migraine, while control subjects could not. Results. 103 subjects were studied, 21 with CVS, 46 with migraine and 36 healthy controls. CVS and migraine did not differ in the relative frequencies of fibromyalgia, OI, syncope, and functional dyspepsia. However, CVS patients did demonstrate a significantly elevated frequency of CRPS. Conclusions. Although CVS and migraine clearly share many of the same comorbidities, they do differ in one important association, suggesting that they may not be identical in pathophysiology. Since OI is common in CVS, treatment strategies could also target this abnormality. |
| format | Article |
| id | doaj-art-5a7b2677534348849ebdc69638914fc9 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-5a7b2677534348849ebdc69638914fc92025-02-03T05:54:09ZengWileyGastroenterology Research and Practice1687-61211687-630X2009-01-01200910.1155/2009/701019701019A Comparison of Dysautonomias Comorbid with Cyclic Vomiting Syndrome and with MigraineGisela Chelimsky0Shruti Madan1Amer Alshekhlee2Elizabeth Heller3Kevin McNeeley4Thomas Chelimsky5Department of Pediatrics, University Hospitals of Cleveland, Cleveland, OH 44106, USARainbow Babies Children's Hospital, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH 44106-6031, USAAutonomic Laboratory, Neurological Institute, Cleveland, OH 44106-6031, USAAutonomic Laboratory, Neurological Institute, Cleveland, OH 44106-6031, USAAutonomic Laboratory, Neurological Institute, Cleveland, OH 44106-6031, USAAutonomic Laboratory, Neurological Institute, Cleveland, OH 44106-6031, USACyclic vomiting syndrome (CVS) shares many features with migraine headache, including auras, photophobia, and antimigrainous treatment response being traditionally viewed as a migraine variant. Aims. To determine whether CVS is associated with the same disorders as migraine headache, and compare these associations to those in healthy control subjects. Methods. Cross-sectional study of patients utilizing the ODYSA instrument, evaluating the probability of 12 functional/autonomic diagnoses, CVS, migraine, orthostatic intolerance (OI), reflex syncope, interstitial cystitis, Raynaud's syndrome, complex regional pain syndrome (CRPS), irritable bowel syndrome, functional dyspepsia, functional abdominal pain, fibromyalgia, and chronic fatigue syndrome. Control subjects were age-matched gender-matched friends. Patients had to fulfill criteria for CVS or migraine, while control subjects could not. Results. 103 subjects were studied, 21 with CVS, 46 with migraine and 36 healthy controls. CVS and migraine did not differ in the relative frequencies of fibromyalgia, OI, syncope, and functional dyspepsia. However, CVS patients did demonstrate a significantly elevated frequency of CRPS. Conclusions. Although CVS and migraine clearly share many of the same comorbidities, they do differ in one important association, suggesting that they may not be identical in pathophysiology. Since OI is common in CVS, treatment strategies could also target this abnormality.http://dx.doi.org/10.1155/2009/701019 |
| spellingShingle | Gisela Chelimsky Shruti Madan Amer Alshekhlee Elizabeth Heller Kevin McNeeley Thomas Chelimsky A Comparison of Dysautonomias Comorbid with Cyclic Vomiting Syndrome and with Migraine Gastroenterology Research and Practice |
| title | A Comparison of Dysautonomias Comorbid with Cyclic Vomiting Syndrome and with Migraine |
| title_full | A Comparison of Dysautonomias Comorbid with Cyclic Vomiting Syndrome and with Migraine |
| title_fullStr | A Comparison of Dysautonomias Comorbid with Cyclic Vomiting Syndrome and with Migraine |
| title_full_unstemmed | A Comparison of Dysautonomias Comorbid with Cyclic Vomiting Syndrome and with Migraine |
| title_short | A Comparison of Dysautonomias Comorbid with Cyclic Vomiting Syndrome and with Migraine |
| title_sort | comparison of dysautonomias comorbid with cyclic vomiting syndrome and with migraine |
| url | http://dx.doi.org/10.1155/2009/701019 |
| work_keys_str_mv | AT giselachelimsky acomparisonofdysautonomiascomorbidwithcyclicvomitingsyndromeandwithmigraine AT shrutimadan acomparisonofdysautonomiascomorbidwithcyclicvomitingsyndromeandwithmigraine AT ameralshekhlee acomparisonofdysautonomiascomorbidwithcyclicvomitingsyndromeandwithmigraine AT elizabethheller acomparisonofdysautonomiascomorbidwithcyclicvomitingsyndromeandwithmigraine AT kevinmcneeley acomparisonofdysautonomiascomorbidwithcyclicvomitingsyndromeandwithmigraine AT thomaschelimsky acomparisonofdysautonomiascomorbidwithcyclicvomitingsyndromeandwithmigraine AT giselachelimsky comparisonofdysautonomiascomorbidwithcyclicvomitingsyndromeandwithmigraine AT shrutimadan comparisonofdysautonomiascomorbidwithcyclicvomitingsyndromeandwithmigraine AT ameralshekhlee comparisonofdysautonomiascomorbidwithcyclicvomitingsyndromeandwithmigraine AT elizabethheller comparisonofdysautonomiascomorbidwithcyclicvomitingsyndromeandwithmigraine AT kevinmcneeley comparisonofdysautonomiascomorbidwithcyclicvomitingsyndromeandwithmigraine AT thomaschelimsky comparisonofdysautonomiascomorbidwithcyclicvomitingsyndromeandwithmigraine |