Risk of death during acute infection is accelerating across diverse host-pathogen systems and consistent with multiple models of host-pathogen interaction

Risk of death during acute infection is accelerating across diverse host-pathogen systems and consistent with multiple models of host-pathogen interaction

ABSTRACT Infectious diseases remain a major cause of global mortality, yet basic questions concerning the relationship between within-host processes governing pathogen burden (pathogen replication, immune responses) and population-scale (epidemiological) patterns of mortality remain obscure. We use...

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Bibliographic Details
Main Authors: Tim O'Sullivan, Canan Karakoç, Kristofer Wollein Waldetoft, Sam P. Brown
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:mSphere
Subjects:
mortality
death
age of infection
meta-analysis
virulence
within-host dynamics
Online Access:https://journals.asm.org/doi/10.1128/msphere.00953-24
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