Mutations in human prion-like domains: pathogenic but not always amyloidogenic
Heterogeneous nuclear ribonucleoproteins (hnRNPs) are multifunctional proteins with integral roles in RNA metabolism and the regulation of alternative splicing. These proteins typically contain prion-like domains of low complexity (PrLDs or LCDs) that govern their assembly into either functional or...
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Main Authors: | Andrea Bartolomé-Nafría, Javier García-Pardo, Salvador Ventura |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2024-12-01
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Series: | Prion |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/19336896.2024.2329186 |
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