Seizure as Presenting Symptom of Multisystem Inflammatory Syndrome in Children
We describe the case of a 13-year-old girl who presented with a new-onset seizure and fever and subsequently developed severe cardiac dysfunction, coronary artery dilation, and shock due to the surprising diagnosis of multisystem inflammatory syndrome in children (MIS-C). Although the clinical entit...
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2023/3581310 |
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| author | Eleonora S. D’Ambrosio Stefanie Gauguet Christine Miller Erin McMahon Christopher Driscoll Mugdha Mohanty Thomas Guggina |
| author_facet | Eleonora S. D’Ambrosio Stefanie Gauguet Christine Miller Erin McMahon Christopher Driscoll Mugdha Mohanty Thomas Guggina |
| author_sort | Eleonora S. D’Ambrosio |
| collection | DOAJ |
| description | We describe the case of a 13-year-old girl who presented with a new-onset seizure and fever and subsequently developed severe cardiac dysfunction, coronary artery dilation, and shock due to the surprising diagnosis of multisystem inflammatory syndrome in children (MIS-C). Although the clinical entity we now call MIS-C was first mentioned in the medical literature in April 2020, the full picture of this disease process is still evolving. Neurologic involvement has been described in cases with MIS-C; however, seizures are not a typical presenting symptom. Additionally, because children infected with SARS-CoV-2 are often asymptomatic, a documented preceding COVID-19 infection might not be available to raise suspicion of MIS-C early on. Febrile seizures, meningitis, and encephalitis are childhood illnesses that pediatricians are generally familiar with, but associating these clinical pictures with MIS-C is uncommon. Given the possibility of rapid clinical cardiogenic decline, as seen in our patient, a prompt diagnosis and appropriate monitoring and treatment are of utmost importance. This case report aims to raise awareness that new-onset seizures with fevers can be early or the first presenting symptoms in children with MIS-C, and further workup and close monitoring may be required. |
| format | Article |
| id | doaj-art-59e1646eacaf44aab7c5fc53b28bb04e |
| institution | Kabale University |
| issn | 2090-6633 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-59e1646eacaf44aab7c5fc53b28bb04e2025-02-03T05:52:24ZengWileyCase Reports in Infectious Diseases2090-66332023-01-01202310.1155/2023/3581310Seizure as Presenting Symptom of Multisystem Inflammatory Syndrome in ChildrenEleonora S. D’Ambrosio0Stefanie Gauguet1Christine Miller2Erin McMahon3Christopher Driscoll4Mugdha Mohanty5Thomas Guggina6Department of NeurologyDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsWe describe the case of a 13-year-old girl who presented with a new-onset seizure and fever and subsequently developed severe cardiac dysfunction, coronary artery dilation, and shock due to the surprising diagnosis of multisystem inflammatory syndrome in children (MIS-C). Although the clinical entity we now call MIS-C was first mentioned in the medical literature in April 2020, the full picture of this disease process is still evolving. Neurologic involvement has been described in cases with MIS-C; however, seizures are not a typical presenting symptom. Additionally, because children infected with SARS-CoV-2 are often asymptomatic, a documented preceding COVID-19 infection might not be available to raise suspicion of MIS-C early on. Febrile seizures, meningitis, and encephalitis are childhood illnesses that pediatricians are generally familiar with, but associating these clinical pictures with MIS-C is uncommon. Given the possibility of rapid clinical cardiogenic decline, as seen in our patient, a prompt diagnosis and appropriate monitoring and treatment are of utmost importance. This case report aims to raise awareness that new-onset seizures with fevers can be early or the first presenting symptoms in children with MIS-C, and further workup and close monitoring may be required.http://dx.doi.org/10.1155/2023/3581310 |
| spellingShingle | Eleonora S. D’Ambrosio Stefanie Gauguet Christine Miller Erin McMahon Christopher Driscoll Mugdha Mohanty Thomas Guggina Seizure as Presenting Symptom of Multisystem Inflammatory Syndrome in Children Case Reports in Infectious Diseases |
| title | Seizure as Presenting Symptom of Multisystem Inflammatory Syndrome in Children |
| title_full | Seizure as Presenting Symptom of Multisystem Inflammatory Syndrome in Children |
| title_fullStr | Seizure as Presenting Symptom of Multisystem Inflammatory Syndrome in Children |
| title_full_unstemmed | Seizure as Presenting Symptom of Multisystem Inflammatory Syndrome in Children |
| title_short | Seizure as Presenting Symptom of Multisystem Inflammatory Syndrome in Children |
| title_sort | seizure as presenting symptom of multisystem inflammatory syndrome in children |
| url | http://dx.doi.org/10.1155/2023/3581310 |
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