Recurrent Cesarean Scar Ectopic Pregnancy Treated with Systemic Methotrexate

Cesarean scar pregnancy (CSP) is a rare event; however its incidence has been rising due to the increasing rates of cesarean deliveries. The majority of cases present with signs or symptoms requiring surgery, which often results in hysterectomy. The recurrence of CSP is even rarer with only few case...

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Main Authors: Chima Ndubizu, Rodney A. McLaren, Sandra McCalla, Mohamad Irani
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2017/9536869
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author Chima Ndubizu
Rodney A. McLaren
Sandra McCalla
Mohamad Irani
author_facet Chima Ndubizu
Rodney A. McLaren
Sandra McCalla
Mohamad Irani
author_sort Chima Ndubizu
collection DOAJ
description Cesarean scar pregnancy (CSP) is a rare event; however its incidence has been rising due to the increasing rates of cesarean deliveries. The majority of cases present with signs or symptoms requiring surgery, which often results in hysterectomy. The recurrence of CSP is even rarer with only few cases which have been reported. This is a report of recurrent cesarean scar ectopic pregnancy (RCSP) that was promptly diagnosed and managed with only systemic methotrexate. This was a 30-year-old woman, with a history of two prior cesarean deliveries followed by a CSP, who presented at 5 weeks and 3 days of gestation for her first prenatal visit. Transvaginal ultrasound revealed a RCSP. Her serum beta-human chorionic gonadotropin (β-hCG) level was 54,295 IU/L. The first CSP, which was diagnosed at a later stage, was treated with uterine artery embolization and systemic methotrexate leading to complete resolution within 10 weeks. The current ectopic was treated with two doses of systemic methotrexate; her serum β-hCG reached undetectable levels within 7 weeks. Thus, patients with a history of prior CSP should be carefully monitored with transvaginal ultrasound during subsequent pregnancies to allow early diagnosis of RCSP, which could then be treated conservatively.
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series Case Reports in Obstetrics and Gynecology
spelling doaj-art-59de76d749c4418fa717771554a9e0552025-02-03T06:13:44ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922017-01-01201710.1155/2017/95368699536869Recurrent Cesarean Scar Ectopic Pregnancy Treated with Systemic MethotrexateChima Ndubizu0Rodney A. McLaren1Sandra McCalla2Mohamad Irani3Department of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn, NY 11219, USADepartment of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn, NY 11219, USADepartment of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn, NY 11219, USARonald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY 10021, USACesarean scar pregnancy (CSP) is a rare event; however its incidence has been rising due to the increasing rates of cesarean deliveries. The majority of cases present with signs or symptoms requiring surgery, which often results in hysterectomy. The recurrence of CSP is even rarer with only few cases which have been reported. This is a report of recurrent cesarean scar ectopic pregnancy (RCSP) that was promptly diagnosed and managed with only systemic methotrexate. This was a 30-year-old woman, with a history of two prior cesarean deliveries followed by a CSP, who presented at 5 weeks and 3 days of gestation for her first prenatal visit. Transvaginal ultrasound revealed a RCSP. Her serum beta-human chorionic gonadotropin (β-hCG) level was 54,295 IU/L. The first CSP, which was diagnosed at a later stage, was treated with uterine artery embolization and systemic methotrexate leading to complete resolution within 10 weeks. The current ectopic was treated with two doses of systemic methotrexate; her serum β-hCG reached undetectable levels within 7 weeks. Thus, patients with a history of prior CSP should be carefully monitored with transvaginal ultrasound during subsequent pregnancies to allow early diagnosis of RCSP, which could then be treated conservatively.http://dx.doi.org/10.1155/2017/9536869
spellingShingle Chima Ndubizu
Rodney A. McLaren
Sandra McCalla
Mohamad Irani
Recurrent Cesarean Scar Ectopic Pregnancy Treated with Systemic Methotrexate
Case Reports in Obstetrics and Gynecology
title Recurrent Cesarean Scar Ectopic Pregnancy Treated with Systemic Methotrexate
title_full Recurrent Cesarean Scar Ectopic Pregnancy Treated with Systemic Methotrexate
title_fullStr Recurrent Cesarean Scar Ectopic Pregnancy Treated with Systemic Methotrexate
title_full_unstemmed Recurrent Cesarean Scar Ectopic Pregnancy Treated with Systemic Methotrexate
title_short Recurrent Cesarean Scar Ectopic Pregnancy Treated with Systemic Methotrexate
title_sort recurrent cesarean scar ectopic pregnancy treated with systemic methotrexate
url http://dx.doi.org/10.1155/2017/9536869
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AT rodneyamclaren recurrentcesareanscarectopicpregnancytreatedwithsystemicmethotrexate
AT sandramccalla recurrentcesareanscarectopicpregnancytreatedwithsystemicmethotrexate
AT mohamadirani recurrentcesareanscarectopicpregnancytreatedwithsystemicmethotrexate