GB18-06, a nanobody targeting GDF15, effectively alleviates weight loss and restores physical function in cachexia models
Cachexia is a complicated metabolic syndrome mainly associated with cancers, characterized by extreme weight loss and muscle wasting. It is a debilitating condition that negatively affects prognosis and survival. However, there is currently no effective pharmacological intervention that can reverse...
Saved in:
Main Authors: | Yu Huang, Jinyong Wang, Xiling Wei, Hui Zhang, Wei Shang, Xiangling Zhang, Lanjiao Zhai, Xi Chen, Huiming Li, Suofu Qin |
---|---|
Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2024-12-01
|
Series: | mAbs |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/19420862.2024.2416453 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Suppressing GDF15 enhances the chemotherapeutic effect of 5 FU on MSI-H CRC by regulating the ferroptosis pathway SLC7A11/GSH/GPX4
by: Zhi min Huang Fu, et al.
Published: (2024-12-01) -
GDF15-mediated enhancement of the Warburg effect sustains multiple myeloma growth via TGFβ signaling pathway
by: Wenjing Xue, et al.
Published: (2025-01-01) -
Phthalate exposure induces microRNA-5010/Nrf2-EGR1/GDF15 signaling expression in prostate cancer
by: Yuh-Shyan Tsai, et al.
Published: (2025-01-01) -
Therapeutic Effects of GDF6-Overexpressing Mesenchymal Stem Cells through Upregulation of the GDF15/SIRT1 Axis in Age-Related Hearing Loss
by: Jiali Liu, et al.
Published: (2025-01-01) -
Visual and High-Efficiency Secretion of SARS-CoV-2 Nanobodies with <i>Escherichia coli</i>
by: Shuai Zhao, et al.
Published: (2025-01-01)