DNA methylation as a contributor to dysregulation of STX6 and other frontotemporal Lobar degeneration genetic risk-associated loci

Abstract Frontotemporal lobar degeneration (FTLD) represents a spectrum of clinically, genetically, and pathologically heterogeneous neurodegenerative disorders. The two major FTLD pathological subgroups are FTLD-TDP and FTLD-tau. While the majority of FTLD cases are sporadic, heterogeneity also exi...

Full description

Saved in:
Bibliographic Details
Main Authors: Naiomi Rambarack, Katherine Fodder, Megha Murthy, Christina Toomey, Rohan de Silva, Peter Heutink, Jack Humphrey, Towfique Raj, Tammaryn Lashley, Conceição Bettencourt
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Acta Neuropathologica Communications
Subjects:
Online Access:https://doi.org/10.1186/s40478-025-02071-3
Tags: Add Tag
No Tags, Be the first to tag this record!