Frequency and Predictors of Self-Reported Hypoglycemia in Insulin-Treated Diabetes
Aims. Hypoglycemia is a limiting factor for achieving stringent glycemic control in diabetes. This study analyzes the frequency and predictors of hypoglycemia in insulin-treated diabetes in an ambulatory setting. Methods. A retrospective chart review was performed to study self-monitored blood gluco...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2017/7425925 |
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| author | Samir Malkani Anupam Kotwal |
| author_facet | Samir Malkani Anupam Kotwal |
| author_sort | Samir Malkani |
| collection | DOAJ |
| description | Aims. Hypoglycemia is a limiting factor for achieving stringent glycemic control in diabetes. This study analyzes the frequency and predictors of hypoglycemia in insulin-treated diabetes in an ambulatory setting. Methods. A retrospective chart review was performed to study self-monitored blood glucose (SMBG) data for 3 months prior to a patient’s HbA1c test. Results. Hypoglycemia occurred more frequently in type 1 than in type 2 diabetes; however, 19% of type 2 diabetes patients did experience at least one episode of severe hypoglycemia. For type 1 diabetes, hypoglycemia had a positive association with glycemic variability and duration of diabetes and a negative association with HbA1c and lowest blood glucose (BG). For type 2 diabetes, a positive association was noted with glycemic variability and a negative association with age and lowest BG. Conclusions. Delineating factors predisposing to hypoglycemia in type 2 diabetes is difficult. Lower HbA1c is a potential predictor of hypoglycemia in type 1 but not in type 2 diabetes. Longer duration of diabetes for type 1 and younger age for type 2 are associated with more hypoglycemia. Glycemic variability portends increased risk for hypoglycemia and should be a focus of further research. |
| format | Article |
| id | doaj-art-599aa46f8f514a79bb7d24794b29f8e5 |
| institution | Kabale University |
| issn | 2314-6745 2314-6753 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-599aa46f8f514a79bb7d24794b29f8e52025-02-03T07:24:44ZengWileyJournal of Diabetes Research2314-67452314-67532017-01-01201710.1155/2017/74259257425925Frequency and Predictors of Self-Reported Hypoglycemia in Insulin-Treated DiabetesSamir Malkani0Anupam Kotwal1Division of Diabetes, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USADivision of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, 200 First Street SW, Mayo 18, Rochester, MN 55905, USAAims. Hypoglycemia is a limiting factor for achieving stringent glycemic control in diabetes. This study analyzes the frequency and predictors of hypoglycemia in insulin-treated diabetes in an ambulatory setting. Methods. A retrospective chart review was performed to study self-monitored blood glucose (SMBG) data for 3 months prior to a patient’s HbA1c test. Results. Hypoglycemia occurred more frequently in type 1 than in type 2 diabetes; however, 19% of type 2 diabetes patients did experience at least one episode of severe hypoglycemia. For type 1 diabetes, hypoglycemia had a positive association with glycemic variability and duration of diabetes and a negative association with HbA1c and lowest blood glucose (BG). For type 2 diabetes, a positive association was noted with glycemic variability and a negative association with age and lowest BG. Conclusions. Delineating factors predisposing to hypoglycemia in type 2 diabetes is difficult. Lower HbA1c is a potential predictor of hypoglycemia in type 1 but not in type 2 diabetes. Longer duration of diabetes for type 1 and younger age for type 2 are associated with more hypoglycemia. Glycemic variability portends increased risk for hypoglycemia and should be a focus of further research.http://dx.doi.org/10.1155/2017/7425925 |
| spellingShingle | Samir Malkani Anupam Kotwal Frequency and Predictors of Self-Reported Hypoglycemia in Insulin-Treated Diabetes Journal of Diabetes Research |
| title | Frequency and Predictors of Self-Reported Hypoglycemia in Insulin-Treated Diabetes |
| title_full | Frequency and Predictors of Self-Reported Hypoglycemia in Insulin-Treated Diabetes |
| title_fullStr | Frequency and Predictors of Self-Reported Hypoglycemia in Insulin-Treated Diabetes |
| title_full_unstemmed | Frequency and Predictors of Self-Reported Hypoglycemia in Insulin-Treated Diabetes |
| title_short | Frequency and Predictors of Self-Reported Hypoglycemia in Insulin-Treated Diabetes |
| title_sort | frequency and predictors of self reported hypoglycemia in insulin treated diabetes |
| url | http://dx.doi.org/10.1155/2017/7425925 |
| work_keys_str_mv | AT samirmalkani frequencyandpredictorsofselfreportedhypoglycemiaininsulintreateddiabetes AT anupamkotwal frequencyandpredictorsofselfreportedhypoglycemiaininsulintreateddiabetes |