Transcranial Magnetic Stimulation with the Maximum Voluntary Muscle Contraction Facilitates Motor Neuron Excitability and Muscle Force
Three trials of transcranial magnetic stimulation (TMS) during the maximum voluntary muscle contraction (MVC) were repeated at 15-minute intervals for 1 hour to examine the effects on motor evoked potentials (MEPs) in the digital muscles and pinching muscle force before and after 4 high-intensity TM...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Neurology Research International |
| Online Access: | http://dx.doi.org/10.1155/2012/847634 |
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| author | Tetsuo Touge Yoshiteru Urai Kazuyo Ikeda Kodai Kume Kazushi Deguchi |
| author_facet | Tetsuo Touge Yoshiteru Urai Kazuyo Ikeda Kodai Kume Kazushi Deguchi |
| author_sort | Tetsuo Touge |
| collection | DOAJ |
| description | Three trials of transcranial magnetic stimulation (TMS) during the maximum voluntary muscle contraction (MVC) were repeated at 15-minute intervals for 1 hour to examine the effects on motor evoked potentials (MEPs) in the digital muscles and pinching muscle force before and after 4 high-intensity TMSs (test 1 condition) or sham TMS (test 2 condition) with MVC. Under the placebo condition, real TMS with MVC was administered only before and 1 hour after the sham TMS with MVC. Magnetic stimulation at the foramen magnum level (FMS) with MVC was performed by the same protocol as that for the test 2 condition. As a result, MEP sizes in the digital muscles significantly increased after TMS with MVC under test conditions compared with the placebo conditions (P<0.05). Pinching muscle force was significantly larger 45 minutes and 1 hour after TMS with MVC under the test conditions than under the placebo condition (P<0.05). FMS significantly decreased MEP amplitudes 60 minutes after the sham TMS with MVC (P<0.005). The present results suggest that intermittently repeated TMS with MVC facilitates motor neuron excitabilities and muscle force. However, further studies are needed to confirm the effects of TMS with MVC and its mechanism. |
| format | Article |
| id | doaj-art-5992d3e81df74a5dbff9038790ebb96c |
| institution | Kabale University |
| issn | 2090-1852 2090-1860 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neurology Research International |
| spelling | doaj-art-5992d3e81df74a5dbff9038790ebb96c2025-02-03T05:53:58ZengWileyNeurology Research International2090-18522090-18602012-01-01201210.1155/2012/847634847634Transcranial Magnetic Stimulation with the Maximum Voluntary Muscle Contraction Facilitates Motor Neuron Excitability and Muscle ForceTetsuo Touge0Yoshiteru Urai1Kazuyo Ikeda2Kodai Kume3Kazushi Deguchi4Health Sciences, School of Nursing, Faculty of Medicine, Kagawa University, Kagawa 761-0793, JapanDepartment of Neurology, Tokyo Metropolitan neurological Hospital, Tokyo, JapanGastroenterology and Neurology, School of Medicine, Faculty of Medicine, Kagawa University, Kagawa, JapanGastroenterology and Neurology, School of Medicine, Faculty of Medicine, Kagawa University, Kagawa, JapanGastroenterology and Neurology, School of Medicine, Faculty of Medicine, Kagawa University, Kagawa, JapanThree trials of transcranial magnetic stimulation (TMS) during the maximum voluntary muscle contraction (MVC) were repeated at 15-minute intervals for 1 hour to examine the effects on motor evoked potentials (MEPs) in the digital muscles and pinching muscle force before and after 4 high-intensity TMSs (test 1 condition) or sham TMS (test 2 condition) with MVC. Under the placebo condition, real TMS with MVC was administered only before and 1 hour after the sham TMS with MVC. Magnetic stimulation at the foramen magnum level (FMS) with MVC was performed by the same protocol as that for the test 2 condition. As a result, MEP sizes in the digital muscles significantly increased after TMS with MVC under test conditions compared with the placebo conditions (P<0.05). Pinching muscle force was significantly larger 45 minutes and 1 hour after TMS with MVC under the test conditions than under the placebo condition (P<0.05). FMS significantly decreased MEP amplitudes 60 minutes after the sham TMS with MVC (P<0.005). The present results suggest that intermittently repeated TMS with MVC facilitates motor neuron excitabilities and muscle force. However, further studies are needed to confirm the effects of TMS with MVC and its mechanism.http://dx.doi.org/10.1155/2012/847634 |
| spellingShingle | Tetsuo Touge Yoshiteru Urai Kazuyo Ikeda Kodai Kume Kazushi Deguchi Transcranial Magnetic Stimulation with the Maximum Voluntary Muscle Contraction Facilitates Motor Neuron Excitability and Muscle Force Neurology Research International |
| title | Transcranial Magnetic Stimulation with the Maximum Voluntary Muscle Contraction Facilitates Motor Neuron Excitability and Muscle Force |
| title_full | Transcranial Magnetic Stimulation with the Maximum Voluntary Muscle Contraction Facilitates Motor Neuron Excitability and Muscle Force |
| title_fullStr | Transcranial Magnetic Stimulation with the Maximum Voluntary Muscle Contraction Facilitates Motor Neuron Excitability and Muscle Force |
| title_full_unstemmed | Transcranial Magnetic Stimulation with the Maximum Voluntary Muscle Contraction Facilitates Motor Neuron Excitability and Muscle Force |
| title_short | Transcranial Magnetic Stimulation with the Maximum Voluntary Muscle Contraction Facilitates Motor Neuron Excitability and Muscle Force |
| title_sort | transcranial magnetic stimulation with the maximum voluntary muscle contraction facilitates motor neuron excitability and muscle force |
| url | http://dx.doi.org/10.1155/2012/847634 |
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