Central Hyperthermia Treated with Bromocriptine
Introduction. Central hyperthermia is common in patients with brain injury. It typically has a rapid onset with high temperatures and marked fluctuations and responds poorly to antibiotics and antipyretics. It is also associated with worse outcomes in the brain injured patient. Recognizing this, it...
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Wiley
2017-01-01
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Series: | Case Reports in Neurological Medicine |
Online Access: | http://dx.doi.org/10.1155/2017/1712083 |
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author | P. Natteru P. George R. Bell P. Nattanmai C. R. Newey |
author_facet | P. Natteru P. George R. Bell P. Nattanmai C. R. Newey |
author_sort | P. Natteru |
collection | DOAJ |
description | Introduction. Central hyperthermia is common in patients with brain injury. It typically has a rapid onset with high temperatures and marked fluctuations and responds poorly to antibiotics and antipyretics. It is also associated with worse outcomes in the brain injured patient. Recognizing this, it is important to aggressively manage it. Case Report. We report a 34-year-old male with a right thalamic hemorrhage extending to the midbrain and into the ventricles. During his admission, he developed intractable fevers with core temperatures as high as 39.3°C. Infectious workup was unremarkable. The fever persisted despite empiric antibiotics, antipyretics, and cooling wraps. Bromocriptine was started resulting in control of the central hyperthermia. The fever spikes were reduced to minor fluctuations that significantly worsened with any attempt to wean off the bromocriptine. Conclusion. Diagnosing and managing central hyperthermia can be challenging. The use of bromocriptine can be beneficial as we have reported. |
format | Article |
id | doaj-art-59790bd8ed394fe0b73633b855394eba |
institution | Kabale University |
issn | 2090-6668 2090-6676 |
language | English |
publishDate | 2017-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Neurological Medicine |
spelling | doaj-art-59790bd8ed394fe0b73633b855394eba2025-02-03T06:00:15ZengWileyCase Reports in Neurological Medicine2090-66682090-66762017-01-01201710.1155/2017/17120831712083Central Hyperthermia Treated with BromocriptineP. Natteru0P. George1R. Bell2P. Nattanmai3C. R. Newey4Department of Neurology, University of Missouri, 5 Hospital Drive, CE 540, Columbia, MO 65211, USADepartment of Neurology, Cerebrovascular Center, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44125, USADepartment of Surgery, Division of Neurosurgery, University of Missouri, 1 Hospital Drive, Columbia, MO 65211, USADepartment of Neurology, University of Missouri, 5 Hospital Drive, CE 540, Columbia, MO 65211, USADepartment of Neurology, University of Missouri, 5 Hospital Drive, CE 540, Columbia, MO 65211, USAIntroduction. Central hyperthermia is common in patients with brain injury. It typically has a rapid onset with high temperatures and marked fluctuations and responds poorly to antibiotics and antipyretics. It is also associated with worse outcomes in the brain injured patient. Recognizing this, it is important to aggressively manage it. Case Report. We report a 34-year-old male with a right thalamic hemorrhage extending to the midbrain and into the ventricles. During his admission, he developed intractable fevers with core temperatures as high as 39.3°C. Infectious workup was unremarkable. The fever persisted despite empiric antibiotics, antipyretics, and cooling wraps. Bromocriptine was started resulting in control of the central hyperthermia. The fever spikes were reduced to minor fluctuations that significantly worsened with any attempt to wean off the bromocriptine. Conclusion. Diagnosing and managing central hyperthermia can be challenging. The use of bromocriptine can be beneficial as we have reported.http://dx.doi.org/10.1155/2017/1712083 |
spellingShingle | P. Natteru P. George R. Bell P. Nattanmai C. R. Newey Central Hyperthermia Treated with Bromocriptine Case Reports in Neurological Medicine |
title | Central Hyperthermia Treated with Bromocriptine |
title_full | Central Hyperthermia Treated with Bromocriptine |
title_fullStr | Central Hyperthermia Treated with Bromocriptine |
title_full_unstemmed | Central Hyperthermia Treated with Bromocriptine |
title_short | Central Hyperthermia Treated with Bromocriptine |
title_sort | central hyperthermia treated with bromocriptine |
url | http://dx.doi.org/10.1155/2017/1712083 |
work_keys_str_mv | AT pnatteru centralhyperthermiatreatedwithbromocriptine AT pgeorge centralhyperthermiatreatedwithbromocriptine AT rbell centralhyperthermiatreatedwithbromocriptine AT pnattanmai centralhyperthermiatreatedwithbromocriptine AT crnewey centralhyperthermiatreatedwithbromocriptine |