Central Hyperthermia Treated with Bromocriptine

Introduction. Central hyperthermia is common in patients with brain injury. It typically has a rapid onset with high temperatures and marked fluctuations and responds poorly to antibiotics and antipyretics. It is also associated with worse outcomes in the brain injured patient. Recognizing this, it...

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Main Authors: P. Natteru, P. George, R. Bell, P. Nattanmai, C. R. Newey
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2017/1712083
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author P. Natteru
P. George
R. Bell
P. Nattanmai
C. R. Newey
author_facet P. Natteru
P. George
R. Bell
P. Nattanmai
C. R. Newey
author_sort P. Natteru
collection DOAJ
description Introduction. Central hyperthermia is common in patients with brain injury. It typically has a rapid onset with high temperatures and marked fluctuations and responds poorly to antibiotics and antipyretics. It is also associated with worse outcomes in the brain injured patient. Recognizing this, it is important to aggressively manage it. Case Report. We report a 34-year-old male with a right thalamic hemorrhage extending to the midbrain and into the ventricles. During his admission, he developed intractable fevers with core temperatures as high as 39.3°C. Infectious workup was unremarkable. The fever persisted despite empiric antibiotics, antipyretics, and cooling wraps. Bromocriptine was started resulting in control of the central hyperthermia. The fever spikes were reduced to minor fluctuations that significantly worsened with any attempt to wean off the bromocriptine. Conclusion. Diagnosing and managing central hyperthermia can be challenging. The use of bromocriptine can be beneficial as we have reported.
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spelling doaj-art-59790bd8ed394fe0b73633b855394eba2025-02-03T06:00:15ZengWileyCase Reports in Neurological Medicine2090-66682090-66762017-01-01201710.1155/2017/17120831712083Central Hyperthermia Treated with BromocriptineP. Natteru0P. George1R. Bell2P. Nattanmai3C. R. Newey4Department of Neurology, University of Missouri, 5 Hospital Drive, CE 540, Columbia, MO 65211, USADepartment of Neurology, Cerebrovascular Center, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44125, USADepartment of Surgery, Division of Neurosurgery, University of Missouri, 1 Hospital Drive, Columbia, MO 65211, USADepartment of Neurology, University of Missouri, 5 Hospital Drive, CE 540, Columbia, MO 65211, USADepartment of Neurology, University of Missouri, 5 Hospital Drive, CE 540, Columbia, MO 65211, USAIntroduction. Central hyperthermia is common in patients with brain injury. It typically has a rapid onset with high temperatures and marked fluctuations and responds poorly to antibiotics and antipyretics. It is also associated with worse outcomes in the brain injured patient. Recognizing this, it is important to aggressively manage it. Case Report. We report a 34-year-old male with a right thalamic hemorrhage extending to the midbrain and into the ventricles. During his admission, he developed intractable fevers with core temperatures as high as 39.3°C. Infectious workup was unremarkable. The fever persisted despite empiric antibiotics, antipyretics, and cooling wraps. Bromocriptine was started resulting in control of the central hyperthermia. The fever spikes were reduced to minor fluctuations that significantly worsened with any attempt to wean off the bromocriptine. Conclusion. Diagnosing and managing central hyperthermia can be challenging. The use of bromocriptine can be beneficial as we have reported.http://dx.doi.org/10.1155/2017/1712083
spellingShingle P. Natteru
P. George
R. Bell
P. Nattanmai
C. R. Newey
Central Hyperthermia Treated with Bromocriptine
Case Reports in Neurological Medicine
title Central Hyperthermia Treated with Bromocriptine
title_full Central Hyperthermia Treated with Bromocriptine
title_fullStr Central Hyperthermia Treated with Bromocriptine
title_full_unstemmed Central Hyperthermia Treated with Bromocriptine
title_short Central Hyperthermia Treated with Bromocriptine
title_sort central hyperthermia treated with bromocriptine
url http://dx.doi.org/10.1155/2017/1712083
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