Effects of Dietary Strawberry Supplementation on Antioxidant Biomarkers in Obese Adults with Above Optimal Serum Lipids
Berries have shown several cardiovascular health benefits and have been associated with antioxidant functions in experimental models. Clinical studies are limited. We examined the antioxidant effects of freeze-dried strawberries (FDS) in adults [n=60; age: 49±10 years; BMI: 36±5 kg/m2 (mean ± SD)] w...
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| Format: | Article |
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Wiley
2016-01-01
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| Series: | Journal of Nutrition and Metabolism |
| Online Access: | http://dx.doi.org/10.1155/2016/3910630 |
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| author | Arpita Basu Stacy Morris Angel Nguyen Nancy M. Betts Dongxu Fu Timothy J. Lyons |
| author_facet | Arpita Basu Stacy Morris Angel Nguyen Nancy M. Betts Dongxu Fu Timothy J. Lyons |
| author_sort | Arpita Basu |
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| description | Berries have shown several cardiovascular health benefits and have been associated with antioxidant functions in experimental models. Clinical studies are limited. We examined the antioxidant effects of freeze-dried strawberries (FDS) in adults [n=60; age: 49±10 years; BMI: 36±5 kg/m2 (mean ± SD)] with abdominal adiposity and elevated serum lipids. Participants were randomized to one of the following arms: low dose strawberry (25 g/day FDS), low dose control beverage (LD-C), high dose strawberry (50 g/d FDS), and high dose control beverage (HD-C) for 12 weeks. Control beverages were matched for calories and total fiber. Plasma antioxidant capacity, trace elements (copper, iron, selenium, and zinc), whole blood glutathione (GSH), and enzyme activity (catalase, glutathione peroxidase, and glutathione reductase) were examined at screening (0 week) and after 12 weeks’ intervention. At 12 weeks, plasma antioxidant capacity and glutathione levels were higher in the strawberry versus control groups (low and high dose FDS: 45% and 42% for plasma antioxidant capacity and 28% and 36% for glutathione, resp.); glutathione was higher in the high versus low dose strawberry group (all p<0.05). Serum catalase activity was higher in the low dose strawberry (43%) versus control group (p<0.01). No differences were noted in plasma trace elements and glutathione enzyme activity. Dietary strawberries may selectively increase plasma antioxidant biomarkers in obese adults with elevated lipids. |
| format | Article |
| id | doaj-art-59574c2b2d984f03a2aaa5843e9ba547 |
| institution | Kabale University |
| issn | 2090-0724 2090-0732 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Nutrition and Metabolism |
| spelling | doaj-art-59574c2b2d984f03a2aaa5843e9ba5472025-02-03T07:24:06ZengWileyJournal of Nutrition and Metabolism2090-07242090-07322016-01-01201610.1155/2016/39106303910630Effects of Dietary Strawberry Supplementation on Antioxidant Biomarkers in Obese Adults with Above Optimal Serum LipidsArpita Basu0Stacy Morris1Angel Nguyen2Nancy M. Betts3Dongxu Fu4Timothy J. Lyons5Department of Nutritional Sciences, College of Human Sciences, Oklahoma State University, Stillwater, OK 74078, USADepartment of Nutritional Sciences, College of Human Sciences, Oklahoma State University, Stillwater, OK 74078, USADepartment of Nutritional Sciences, College of Human Sciences, Oklahoma State University, Stillwater, OK 74078, USADepartment of Nutritional Sciences, College of Human Sciences, Oklahoma State University, Stillwater, OK 74078, USACentre for Experimental Medicine, Queen’s University of Belfast, Belfast BT7 1NN, UKCentre for Experimental Medicine, Queen’s University of Belfast, Belfast BT7 1NN, UKBerries have shown several cardiovascular health benefits and have been associated with antioxidant functions in experimental models. Clinical studies are limited. We examined the antioxidant effects of freeze-dried strawberries (FDS) in adults [n=60; age: 49±10 years; BMI: 36±5 kg/m2 (mean ± SD)] with abdominal adiposity and elevated serum lipids. Participants were randomized to one of the following arms: low dose strawberry (25 g/day FDS), low dose control beverage (LD-C), high dose strawberry (50 g/d FDS), and high dose control beverage (HD-C) for 12 weeks. Control beverages were matched for calories and total fiber. Plasma antioxidant capacity, trace elements (copper, iron, selenium, and zinc), whole blood glutathione (GSH), and enzyme activity (catalase, glutathione peroxidase, and glutathione reductase) were examined at screening (0 week) and after 12 weeks’ intervention. At 12 weeks, plasma antioxidant capacity and glutathione levels were higher in the strawberry versus control groups (low and high dose FDS: 45% and 42% for plasma antioxidant capacity and 28% and 36% for glutathione, resp.); glutathione was higher in the high versus low dose strawberry group (all p<0.05). Serum catalase activity was higher in the low dose strawberry (43%) versus control group (p<0.01). No differences were noted in plasma trace elements and glutathione enzyme activity. Dietary strawberries may selectively increase plasma antioxidant biomarkers in obese adults with elevated lipids.http://dx.doi.org/10.1155/2016/3910630 |
| spellingShingle | Arpita Basu Stacy Morris Angel Nguyen Nancy M. Betts Dongxu Fu Timothy J. Lyons Effects of Dietary Strawberry Supplementation on Antioxidant Biomarkers in Obese Adults with Above Optimal Serum Lipids Journal of Nutrition and Metabolism |
| title | Effects of Dietary Strawberry Supplementation on Antioxidant Biomarkers in Obese Adults with Above Optimal Serum Lipids |
| title_full | Effects of Dietary Strawberry Supplementation on Antioxidant Biomarkers in Obese Adults with Above Optimal Serum Lipids |
| title_fullStr | Effects of Dietary Strawberry Supplementation on Antioxidant Biomarkers in Obese Adults with Above Optimal Serum Lipids |
| title_full_unstemmed | Effects of Dietary Strawberry Supplementation on Antioxidant Biomarkers in Obese Adults with Above Optimal Serum Lipids |
| title_short | Effects of Dietary Strawberry Supplementation on Antioxidant Biomarkers in Obese Adults with Above Optimal Serum Lipids |
| title_sort | effects of dietary strawberry supplementation on antioxidant biomarkers in obese adults with above optimal serum lipids |
| url | http://dx.doi.org/10.1155/2016/3910630 |
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