Resistance-Associated Substitutions (RAS) and Clinical Factors as Determinants of Sofosbuvir-Daclatasvir Treatment Outcomes in Chronic Hepatitis C Patients

Resistance-Associated Substitutions (RAS) and Clinical Factors as Determinants of Sofosbuvir-Daclatasvir Treatment Outcomes in Chronic Hepatitis C Patients

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Background: Direct acting antivirals (DAAs) have demonstrated remarkable efficacy, in achieving hepatitis C viral (HCV) elimination rates higher than 90%. One particular concern associated with treatment failure is the emergence of resistance associated substitutions (RASs) in the genome. The occurr...

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Bibliographic Details
Main Authors: Juferdy Kurniawan, Anugrah Dwi Handayu, Gita Aprilicia, Darlene Raudhatul Bahri, Irsan Hasan
Format: Article
Language:English
Published: Interna Publishing 2024-10-01
Series:Acta Medica Indonesiana
Subjects:
hepatitis c
direct acting antiviral
resistance associated substitutions
mutation
y93h region
Online Access:https://actamedindones.org/index.php/ijim/article/view/2625
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