Midline 1 associated with Fas signaling enhances murine antigen-induced arthritis

Midline 1 associated with Fas signaling enhances murine antigen-induced arthritis

IntroductionRheumatoid arthritis is the most common immune-mediated joint disease, whose pathogenesis includes both innate and acquired immune mechanisms. Fas/Fas ligand system is considered to have a dual role in arthritis, inducing apoptotic cell death of hyperplastic synoviocytes and inflammatory...

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Main Authors: Nina Lukač, Darja Flegar, Sara Priselac, Tomislav Kelava, Alan Šućur, Maša Filipović, Dino Šisl, Martina Fadljević, Igor Radanović, Vedran Katavić, Nives Zimmermann, Danka Grčević, Nataša Kovačić
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
rheumatoid arthritis
myeloid lineage
midline 1
Fas
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1451093/full
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