Decreased Responsiveness to Chemical Itch in Old Mice

Aging is associated with altered itch perception, potentially due to changes in neuronal function and pruriceptive signaling. The underlying mechanisms, however, remain unclear. We investigated age-related differences in itch sensitivity at behavioral, cellular, and molecular levels. Young and old m...

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Bibliographic Details
Main Authors: Qiaofeng Zhao, Mitsutoshi Tominaga, Sumika Toyama, Kotaro Honda, Eriko Komiya, Yayoi Kamata, Hang Ma, Kenji Takamori
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
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Online Access:https://www.mdpi.com/2073-4409/14/12/889
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