Comparison of RNA- and DNA-based 16S amplicon sequencing to find the optimal approach for the analysis of the uterine microbiome

Abstract Studies in humans and large animals indicate a relationship between the uterine microbiome composition and endometrial receptivity. Despite many studies have been performed, the analysis of the uterine microbiome remains challenging due to the very low microbial biomass. Studies in other bi...

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Bibliographic Details
Main Authors: Antonia I. Dyroff, Álvaro López-Valiñas, Humberto B. Magalhaes, Giorgia Podico, Igor F. Canisso, Carmen Almiñana, Stefan Bauersachs
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-00969-5
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