Studying sex differences in responses to fibroblast growth factor 21 administration in obese mice consuming a sweet-fat diet

Studying sex differences in responses to fibroblast growth factor 21 administration in obese mice consuming a sweet-fat diet

In animals, obesity caused by consumption of a sweet-fat diet (SFD) is the most adequate mouse model of human diet-induced obesity. Fibroblast growth factor 21 (FGF21) reduces body weight, beneficially affects taste preferences, and corrects glucose metabolism in obese mice. Sex is known to influenc...

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Bibliographic Details
Main Authors: N. М. Bazhan, T. V. Jakovleva, A. Yu. Kazantseva, N. E. Kostina, P. E. Orlov, N. Yu. Balybina, K. О. Baranov, E. N. Makarova
Format: Article
Language:English
Published: Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2023-07-01
Series:Вавиловский журнал генетики и селекции
Subjects:
fgf21
obesity
sex differences
liver
adipose tissue
hypothalamus
food intake
gene expression
Online Access:https://vavilov.elpub.ru/jour/article/view/3771
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