GH inhibits ALV-J replication and restricts cell cycle by activating PI3K/Akt signaling pathway

GH inhibits ALV-J replication and restricts cell cycle by activating PI3K/Akt signaling pathway

Growth hormone (GH) plays a crucial role in growth, sexual maturity, and immunity in chickens. Avian leukosis virus subgroup J (ALV-J) is an exogenous tumorigenic retrovirus that primarily induces immunosuppression, growth retardation, decreased egg production, tumors formation, and even death in ch...

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Bibliographic Details
Main Authors: Junliang Xia, Ling Lin, Rongyang Ju, Chengxun Xu, Guodong Mo, Xiquan Zhang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Poultry Science
Subjects:
J subgroup avian leukosis virus
Growth hormone
PI3K/Akt signaling pathway
Cell proliferation
Cell apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579124010927
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