Benzocaine-Induced Methemoglobinemia in a Postoperative Bariatric Patient following Esophagogastroduodenoscopy

Methemoglobinemia is a rare complication in clinical practice. It is most commonly seen in patients undergoing endoscopic procedures, including EGDs, laryngoscopies, bronchoscopies, and nasogastric tube insertions. This is thought to be a disease seen almost exclusively in patients with genetic pred...

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Main Authors: Khuram Khan, Irwin White-Gittens, Saqib Saeed, Leaque Ahmed
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2019/1571423
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author Khuram Khan
Irwin White-Gittens
Saqib Saeed
Leaque Ahmed
author_facet Khuram Khan
Irwin White-Gittens
Saqib Saeed
Leaque Ahmed
author_sort Khuram Khan
collection DOAJ
description Methemoglobinemia is a rare complication in clinical practice. It is most commonly seen in patients undergoing endoscopic procedures, including EGDs, laryngoscopies, bronchoscopies, and nasogastric tube insertions. This is thought to be a disease seen almost exclusively in patients with genetic predispositions to develop it; the increasing use of topical anesthetics during procedures has made methemoglobinemia a disease entity that every clinical provider should be able to recognize and treat. Clinically, patients become cyanotic with mild oxygen derangements on pulse oximetry, in the range of 84 to 90%. Paradoxically, these patients demonstrate normal to supranormal oxygen levels in the blood on blood gas analysis. We report a case of 34-year-old female postoperative Roux-en-Y gastric bypass patient who developed hypoxia and cyanosis after a routine EGD procedure to relieve a food impaction. Differentials of aspiration and pulmonary embolism were plausible; stat blood gas analysis clinched the diagnosis and managed with intravenous methylene blue.
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institution Kabale University
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publishDate 2019-01-01
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spelling doaj-art-58e0c4ed6ba34c84a28324169ca4ef9e2025-02-03T05:57:12ZengWileyCase Reports in Critical Care2090-64202090-64392019-01-01201910.1155/2019/15714231571423Benzocaine-Induced Methemoglobinemia in a Postoperative Bariatric Patient following EsophagogastroduodenoscopyKhuram Khan0Irwin White-Gittens1Saqib Saeed2Leaque Ahmed3Department of Surgery, Harlem Hospital Center, Columbia University Medical Center, New York, NY, USADepartment of Surgery, Harlem Hospital Center, Columbia University Medical Center, New York, NY, USADepartment of Surgery, Harlem Hospital Center, Columbia University Medical Center, New York, NY, USADepartment of Surgery, Harlem Hospital Center, Columbia University Medical Center, New York, NY, USAMethemoglobinemia is a rare complication in clinical practice. It is most commonly seen in patients undergoing endoscopic procedures, including EGDs, laryngoscopies, bronchoscopies, and nasogastric tube insertions. This is thought to be a disease seen almost exclusively in patients with genetic predispositions to develop it; the increasing use of topical anesthetics during procedures has made methemoglobinemia a disease entity that every clinical provider should be able to recognize and treat. Clinically, patients become cyanotic with mild oxygen derangements on pulse oximetry, in the range of 84 to 90%. Paradoxically, these patients demonstrate normal to supranormal oxygen levels in the blood on blood gas analysis. We report a case of 34-year-old female postoperative Roux-en-Y gastric bypass patient who developed hypoxia and cyanosis after a routine EGD procedure to relieve a food impaction. Differentials of aspiration and pulmonary embolism were plausible; stat blood gas analysis clinched the diagnosis and managed with intravenous methylene blue.http://dx.doi.org/10.1155/2019/1571423
spellingShingle Khuram Khan
Irwin White-Gittens
Saqib Saeed
Leaque Ahmed
Benzocaine-Induced Methemoglobinemia in a Postoperative Bariatric Patient following Esophagogastroduodenoscopy
Case Reports in Critical Care
title Benzocaine-Induced Methemoglobinemia in a Postoperative Bariatric Patient following Esophagogastroduodenoscopy
title_full Benzocaine-Induced Methemoglobinemia in a Postoperative Bariatric Patient following Esophagogastroduodenoscopy
title_fullStr Benzocaine-Induced Methemoglobinemia in a Postoperative Bariatric Patient following Esophagogastroduodenoscopy
title_full_unstemmed Benzocaine-Induced Methemoglobinemia in a Postoperative Bariatric Patient following Esophagogastroduodenoscopy
title_short Benzocaine-Induced Methemoglobinemia in a Postoperative Bariatric Patient following Esophagogastroduodenoscopy
title_sort benzocaine induced methemoglobinemia in a postoperative bariatric patient following esophagogastroduodenoscopy
url http://dx.doi.org/10.1155/2019/1571423
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AT saqibsaeed benzocaineinducedmethemoglobinemiainapostoperativebariatricpatientfollowingesophagogastroduodenoscopy
AT leaqueahmed benzocaineinducedmethemoglobinemiainapostoperativebariatricpatientfollowingesophagogastroduodenoscopy