An Osteolytic Metastasis of Humerus from an Asymptomatic Squamous Cell Carcinoma of Lung: A Rare Clinical Entity

Advanced lung cancer is complicated by skeletal metastases either due to direct extension from adjacent primaries or, more commonly, due to haematogenous dissemination of neoplastic cells. Lumber spine is the most common site for bony metastases in bronchogenic carcinoma. Proximal lone bones, especi...

Full description

Saved in:
Bibliographic Details
Main Authors: Anirban Das, Sudipta Pandit, Sibes k. Das, Sumitra Basuthakur, Somnath Das
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Pulmonology
Online Access:http://dx.doi.org/10.1155/2014/636017
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832555920989618176
author Anirban Das
Sudipta Pandit
Sibes k. Das
Sumitra Basuthakur
Somnath Das
author_facet Anirban Das
Sudipta Pandit
Sibes k. Das
Sumitra Basuthakur
Somnath Das
author_sort Anirban Das
collection DOAJ
description Advanced lung cancer is complicated by skeletal metastases either due to direct extension from adjacent primaries or, more commonly, due to haematogenous dissemination of neoplastic cells. Lumber spine is the most common site for bony metastases in bronchogenic carcinoma. Proximal lone bones, especially humerus, are unusual sites for metastases from lung primaries. Small cell and large cell varieties of lung cancer are most commonly associated with skeletal dissemination. It is also unusual that an asymptomatic squamous cell carcinoma of lung presents with painful, soft tissue swelling with osteolytic metastasis of humerus which is reported in our case. Systemic cytotoxic chemotherapy, local palliative radiotherapy, adequate analgesia, and internal fixation of the affected long bone are different modalities of treatment in this advanced stage of disease. But the prognosis is definitely poor in this stage IV disease.
format Article
id doaj-art-588d72cd725a4a04a1c3581c12c65991
institution Kabale University
issn 2090-6846
2090-6854
language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series Case Reports in Pulmonology
spelling doaj-art-588d72cd725a4a04a1c3581c12c659912025-02-03T05:46:50ZengWileyCase Reports in Pulmonology2090-68462090-68542014-01-01201410.1155/2014/636017636017An Osteolytic Metastasis of Humerus from an Asymptomatic Squamous Cell Carcinoma of Lung: A Rare Clinical EntityAnirban Das0Sudipta Pandit1Sibes k. Das2Sumitra Basuthakur3Somnath Das4Department of Pulmonary Medicine, Medical College, 88 College Street, Kolkata, West Bengal 700 073, IndiaDepartment of Pulmonary Medicine, Medical College, 88 College Street, Kolkata, West Bengal 700 073, IndiaDepartment of Pulmonary Medicine, Medical College, 88 College Street, Kolkata, West Bengal 700 073, IndiaDepartment of Pulmonary Medicine, Medical College, 88 College Street, Kolkata, West Bengal 700 073, IndiaDepartment of Pulmonary Medicine, Medical College, 88 College Street, Kolkata, West Bengal 700 073, IndiaAdvanced lung cancer is complicated by skeletal metastases either due to direct extension from adjacent primaries or, more commonly, due to haematogenous dissemination of neoplastic cells. Lumber spine is the most common site for bony metastases in bronchogenic carcinoma. Proximal lone bones, especially humerus, are unusual sites for metastases from lung primaries. Small cell and large cell varieties of lung cancer are most commonly associated with skeletal dissemination. It is also unusual that an asymptomatic squamous cell carcinoma of lung presents with painful, soft tissue swelling with osteolytic metastasis of humerus which is reported in our case. Systemic cytotoxic chemotherapy, local palliative radiotherapy, adequate analgesia, and internal fixation of the affected long bone are different modalities of treatment in this advanced stage of disease. But the prognosis is definitely poor in this stage IV disease.http://dx.doi.org/10.1155/2014/636017
spellingShingle Anirban Das
Sudipta Pandit
Sibes k. Das
Sumitra Basuthakur
Somnath Das
An Osteolytic Metastasis of Humerus from an Asymptomatic Squamous Cell Carcinoma of Lung: A Rare Clinical Entity
Case Reports in Pulmonology
title An Osteolytic Metastasis of Humerus from an Asymptomatic Squamous Cell Carcinoma of Lung: A Rare Clinical Entity
title_full An Osteolytic Metastasis of Humerus from an Asymptomatic Squamous Cell Carcinoma of Lung: A Rare Clinical Entity
title_fullStr An Osteolytic Metastasis of Humerus from an Asymptomatic Squamous Cell Carcinoma of Lung: A Rare Clinical Entity
title_full_unstemmed An Osteolytic Metastasis of Humerus from an Asymptomatic Squamous Cell Carcinoma of Lung: A Rare Clinical Entity
title_short An Osteolytic Metastasis of Humerus from an Asymptomatic Squamous Cell Carcinoma of Lung: A Rare Clinical Entity
title_sort osteolytic metastasis of humerus from an asymptomatic squamous cell carcinoma of lung a rare clinical entity
url http://dx.doi.org/10.1155/2014/636017
work_keys_str_mv AT anirbandas anosteolyticmetastasisofhumerusfromanasymptomaticsquamouscellcarcinomaoflungarareclinicalentity
AT sudiptapandit anosteolyticmetastasisofhumerusfromanasymptomaticsquamouscellcarcinomaoflungarareclinicalentity
AT sibeskdas anosteolyticmetastasisofhumerusfromanasymptomaticsquamouscellcarcinomaoflungarareclinicalentity
AT sumitrabasuthakur anosteolyticmetastasisofhumerusfromanasymptomaticsquamouscellcarcinomaoflungarareclinicalentity
AT somnathdas anosteolyticmetastasisofhumerusfromanasymptomaticsquamouscellcarcinomaoflungarareclinicalentity
AT anirbandas osteolyticmetastasisofhumerusfromanasymptomaticsquamouscellcarcinomaoflungarareclinicalentity
AT sudiptapandit osteolyticmetastasisofhumerusfromanasymptomaticsquamouscellcarcinomaoflungarareclinicalentity
AT sibeskdas osteolyticmetastasisofhumerusfromanasymptomaticsquamouscellcarcinomaoflungarareclinicalentity
AT sumitrabasuthakur osteolyticmetastasisofhumerusfromanasymptomaticsquamouscellcarcinomaoflungarareclinicalentity
AT somnathdas osteolyticmetastasisofhumerusfromanasymptomaticsquamouscellcarcinomaoflungarareclinicalentity