Genome-Wide Association Study of Hepatitis in Korean Populations
Hepatitis is a common and serious disease for the Korean population. It is caused by a virus, the A and B types of which are plentiful in Koreans. In this study, we tried to find genetic factors for hepatitis through genome-wide association studies. We took 368 cases and 1,500 controls from Anseong...
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| Format: | Article |
| Language: | English |
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BioMed Central
2014-12-01
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| Series: | Genomics & Informatics |
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| Online Access: | http://genominfo.org/upload/pdf/gni-12-203.pdf |
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| author | Youngbok Hong Sejong Oh |
| author_facet | Youngbok Hong Sejong Oh |
| author_sort | Youngbok Hong |
| collection | DOAJ |
| description | Hepatitis is a common and serious disease for the Korean population. It is caused by a virus, the A and B types of which are plentiful in Koreans. In this study, we tried to find genetic factors for hepatitis through genome-wide association studies. We took 368 cases and 1,500 controls from Anseong and Ansan cohort data. About 300,000 single-nucleotide polymorphisms and 20 epidemiological variables were analyzed. We did not find any meaningful significant single nucleotide polymorphisms, but we confirmed the influence of major epidemiological variables on hepatitis. |
| format | Article |
| id | doaj-art-5882f8a78b9a473d8f884d55457e83fd |
| institution | Kabale University |
| issn | 1598-866X 2234-0742 |
| language | English |
| publishDate | 2014-12-01 |
| publisher | BioMed Central |
| record_format | Article |
| series | Genomics & Informatics |
| spelling | doaj-art-5882f8a78b9a473d8f884d55457e83fd2025-02-02T11:33:57ZengBioMed CentralGenomics & Informatics1598-866X2234-07422014-12-0112420320710.5808/GI.2014.12.4.203112Genome-Wide Association Study of Hepatitis in Korean PopulationsYoungbok Hong0Sejong Oh1Department of Nanobiomedical Science, Dankook University, Cheonan 330-714, Korea.Department of Nanobiomedical Science, Dankook University, Cheonan 330-714, Korea.Hepatitis is a common and serious disease for the Korean population. It is caused by a virus, the A and B types of which are plentiful in Koreans. In this study, we tried to find genetic factors for hepatitis through genome-wide association studies. We took 368 cases and 1,500 controls from Anseong and Ansan cohort data. About 300,000 single-nucleotide polymorphisms and 20 epidemiological variables were analyzed. We did not find any meaningful significant single nucleotide polymorphisms, but we confirmed the influence of major epidemiological variables on hepatitis.http://genominfo.org/upload/pdf/gni-12-203.pdfcohort analysisgenome-wide association studyhepatitis |
| spellingShingle | Youngbok Hong Sejong Oh Genome-Wide Association Study of Hepatitis in Korean Populations Genomics & Informatics cohort analysis genome-wide association study hepatitis |
| title | Genome-Wide Association Study of Hepatitis in Korean Populations |
| title_full | Genome-Wide Association Study of Hepatitis in Korean Populations |
| title_fullStr | Genome-Wide Association Study of Hepatitis in Korean Populations |
| title_full_unstemmed | Genome-Wide Association Study of Hepatitis in Korean Populations |
| title_short | Genome-Wide Association Study of Hepatitis in Korean Populations |
| title_sort | genome wide association study of hepatitis in korean populations |
| topic | cohort analysis genome-wide association study hepatitis |
| url | http://genominfo.org/upload/pdf/gni-12-203.pdf |
| work_keys_str_mv | AT youngbokhong genomewideassociationstudyofhepatitisinkoreanpopulations AT sejongoh genomewideassociationstudyofhepatitisinkoreanpopulations |