A feasibility double-blind trial of levothyroxine vs. levothyroxine-liothyronine in postsurgical hypothyroidism

A feasibility double-blind trial of levothyroxine vs. levothyroxine-liothyronine in postsurgical hypothyroidism

ContextDespite normalization of Thyrotropin (TSH), some patients with hypothyroidism treated with Levothyroxine (LT4) report residual symptoms which may be attributable to loss of endogenous triiodothyronine (T3).ObjectiveFeasibility trial LT4/liothyronine (LT3) combination vs. LT4/placebo in post-s...

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Bibliographic Details
Main Authors: Giao Q. Phan, Sahzene Yavuz, Angeliki M. Stamatouli, Ritu Madan, Shanshan Chen, Amelia C. Grover, Naris Nilubol, Pablo Bedoya, Cory Trankle, Roshanak Markley, Antonio Abbate, Francesco S. Celi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Endocrinology
Subjects:
hypothyroidism
post-surgical hypothyroidism
combination therapy
clinical trial
levothyroxine
liothyronine
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1522753/full
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