Lower respiratory tract microbiome dysbiosis impairs clinical responses to immune checkpoint blockade in advanced non‐small‐cell lung cancer

Lower respiratory tract microbiome dysbiosis impairs clinical responses to immune checkpoint blockade in advanced non‐small‐cell lung cancer

Abstract Background Gut microbiome on predicting clinical responses to immune checkpoint inhibitors (ICIs) has been discussed in detail for decades, while microecological features of the lower respiratory tract within advanced non‐small‐cell lung cancer (NSCLC) are still relatively vague. Methods Du...

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Bibliographic Details
Main Authors: Yong Zhang, Xiang‐Xiang Chen, Ruo Chen, Ling Li, Qing Ju, Dan Qiu, Yuan Wang, Peng‐Yu Jing, Ning Chang, Min Wang, Jian Zhang, Zhi‐Nan Chen, Ke Wang
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Clinical and Translational Medicine
Subjects:
advanced non‐small‐cell lung cancer
clinical outcomes
immune checkpoint blockade therapy
lower respiratory tract microbiome
multi‐omics analysis
Online Access:https://doi.org/10.1002/ctm2.70170
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