Trifluoroacetic Acid as an Effective Catalyst for Biginelli Reaction: One-Pot, Three-Component Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (and-Thiones)
Trifluoroacetic acid (TFA) is introduced as an effective catalyst for promotion of Biginelli reaction. 3,4-Dihydropyrimidin-2(1H)-one (-thione) derivatives (DHPMs) were simply and efficiently prepared using TFA catalyzed one-pot, three-component condensation β-dicarbonyl compounds, aldehydes and ure...
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Format: | Article |
Language: | English |
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Wiley
2011-01-01
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Series: | E-Journal of Chemistry |
Online Access: | http://dx.doi.org/10.1155/2011/751282 |
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author | Mohammad R. Mohammadizadeh Neda Firoozi |
author_facet | Mohammad R. Mohammadizadeh Neda Firoozi |
author_sort | Mohammad R. Mohammadizadeh |
collection | DOAJ |
description | Trifluoroacetic acid (TFA) is introduced as an effective catalyst for promotion of Biginelli reaction. 3,4-Dihydropyrimidin-2(1H)-one (-thione) derivatives (DHPMs) were simply and efficiently prepared using TFA catalyzed one-pot, three-component condensation β-dicarbonyl compounds, aldehydes and urea (thio). |
format | Article |
id | doaj-art-5867442b3bf6409e9d1457cf65a5a653 |
institution | Kabale University |
issn | 0973-4945 2090-9810 |
language | English |
publishDate | 2011-01-01 |
publisher | Wiley |
record_format | Article |
series | E-Journal of Chemistry |
spelling | doaj-art-5867442b3bf6409e9d1457cf65a5a6532025-02-03T01:32:47ZengWileyE-Journal of Chemistry0973-49452090-98102011-01-018S1S266S27010.1155/2011/751282Trifluoroacetic Acid as an Effective Catalyst for Biginelli Reaction: One-Pot, Three-Component Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (and-Thiones)Mohammad R. Mohammadizadeh0Neda Firoozi1Department of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr 75169, IranDepartment of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr 75169, IranTrifluoroacetic acid (TFA) is introduced as an effective catalyst for promotion of Biginelli reaction. 3,4-Dihydropyrimidin-2(1H)-one (-thione) derivatives (DHPMs) were simply and efficiently prepared using TFA catalyzed one-pot, three-component condensation β-dicarbonyl compounds, aldehydes and urea (thio).http://dx.doi.org/10.1155/2011/751282 |
spellingShingle | Mohammad R. Mohammadizadeh Neda Firoozi Trifluoroacetic Acid as an Effective Catalyst for Biginelli Reaction: One-Pot, Three-Component Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (and-Thiones) E-Journal of Chemistry |
title | Trifluoroacetic Acid as an Effective Catalyst for Biginelli Reaction: One-Pot, Three-Component Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (and-Thiones) |
title_full | Trifluoroacetic Acid as an Effective Catalyst for Biginelli Reaction: One-Pot, Three-Component Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (and-Thiones) |
title_fullStr | Trifluoroacetic Acid as an Effective Catalyst for Biginelli Reaction: One-Pot, Three-Component Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (and-Thiones) |
title_full_unstemmed | Trifluoroacetic Acid as an Effective Catalyst for Biginelli Reaction: One-Pot, Three-Component Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (and-Thiones) |
title_short | Trifluoroacetic Acid as an Effective Catalyst for Biginelli Reaction: One-Pot, Three-Component Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (and-Thiones) |
title_sort | trifluoroacetic acid as an effective catalyst for biginelli reaction one pot three component synthesis of 3 4 dihydropyrimidin 2 1h ones and thiones |
url | http://dx.doi.org/10.1155/2011/751282 |
work_keys_str_mv | AT mohammadrmohammadizadeh trifluoroaceticacidasaneffectivecatalystforbiginellireactiononepotthreecomponentsynthesisof34dihydropyrimidin21honesandthiones AT nedafiroozi trifluoroaceticacidasaneffectivecatalystforbiginellireactiononepotthreecomponentsynthesisof34dihydropyrimidin21honesandthiones |