Tirofiban-Induced Thrombocytopenia Occurring with Crohn’s Disease
A 69-year-old man, with severe refractory Crohn’s disease, presented with acute coronary syndrome that required angioplasty. He developed severe tirofiban-induced thrombocytopenia (TIT) heralded by type I allergic reaction that required steroids and a combination of antihistamine H1 and antihistamin...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
|
| Series: | Case Reports in Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2016/4605139 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832559073081425920 |
|---|---|
| author | Toni Ibrahim Fady El Karak Assem Araji Elie El Rassy |
| author_facet | Toni Ibrahim Fady El Karak Assem Araji Elie El Rassy |
| author_sort | Toni Ibrahim |
| collection | DOAJ |
| description | A 69-year-old man, with severe refractory Crohn’s disease, presented with acute coronary syndrome that required angioplasty. He developed severe tirofiban-induced thrombocytopenia (TIT) heralded by type I allergic reaction that required steroids and a combination of antihistamine H1 and antihistamine H2 for symptomatic management. The thrombocytopenia spontaneously resolved uneventfully in 48 hours thereafter. This case report suggests a possible association between TIT and inflammatory bowel disease. Therefore, strict monitoring of the platelet count is required in patients who develop allergic reactions to tirofiban. |
| format | Article |
| id | doaj-art-585de8474cd1458ba9bc83c1db6ea375 |
| institution | Kabale University |
| issn | 2090-6404 2090-6412 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Cardiology |
| spelling | doaj-art-585de8474cd1458ba9bc83c1db6ea3752025-02-03T01:30:50ZengWileyCase Reports in Cardiology2090-64042090-64122016-01-01201610.1155/2016/46051394605139Tirofiban-Induced Thrombocytopenia Occurring with Crohn’s DiseaseToni Ibrahim0Fady El Karak1Assem Araji2Elie El Rassy3Department of Cardiology, Bekaa Hospital, Zahle, LebanonDepartment of Cardiology, Bekaa Hospital, Zahle, LebanonDepartment of Cardiology, Bekaa Hospital, Zahle, LebanonDepartment of Hematology, Hôtel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, Beirut, LebanonA 69-year-old man, with severe refractory Crohn’s disease, presented with acute coronary syndrome that required angioplasty. He developed severe tirofiban-induced thrombocytopenia (TIT) heralded by type I allergic reaction that required steroids and a combination of antihistamine H1 and antihistamine H2 for symptomatic management. The thrombocytopenia spontaneously resolved uneventfully in 48 hours thereafter. This case report suggests a possible association between TIT and inflammatory bowel disease. Therefore, strict monitoring of the platelet count is required in patients who develop allergic reactions to tirofiban.http://dx.doi.org/10.1155/2016/4605139 |
| spellingShingle | Toni Ibrahim Fady El Karak Assem Araji Elie El Rassy Tirofiban-Induced Thrombocytopenia Occurring with Crohn’s Disease Case Reports in Cardiology |
| title | Tirofiban-Induced Thrombocytopenia Occurring with Crohn’s Disease |
| title_full | Tirofiban-Induced Thrombocytopenia Occurring with Crohn’s Disease |
| title_fullStr | Tirofiban-Induced Thrombocytopenia Occurring with Crohn’s Disease |
| title_full_unstemmed | Tirofiban-Induced Thrombocytopenia Occurring with Crohn’s Disease |
| title_short | Tirofiban-Induced Thrombocytopenia Occurring with Crohn’s Disease |
| title_sort | tirofiban induced thrombocytopenia occurring with crohn s disease |
| url | http://dx.doi.org/10.1155/2016/4605139 |
| work_keys_str_mv | AT toniibrahim tirofibaninducedthrombocytopeniaoccurringwithcrohnsdisease AT fadyelkarak tirofibaninducedthrombocytopeniaoccurringwithcrohnsdisease AT assemaraji tirofibaninducedthrombocytopeniaoccurringwithcrohnsdisease AT elieelrassy tirofibaninducedthrombocytopeniaoccurringwithcrohnsdisease |