Clinical Outcome of a Novel Anti-CD6 Biologic Itolizumab in Patients of Psoriasis with Comorbid Conditions
Psoriasis is a common, chronic, immune mediated, inflammatory disease of skin characterized by red patches enclosed with white scales and affects 2-3% of people in the world. Topical therapy, phototherapy, and systemic therapy were employed for management of disease from many last decades. However,...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
|
| Series: | Dermatology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2016/1316326 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832552432636264448 |
|---|---|
| author | Vinay Singh |
| author_facet | Vinay Singh |
| author_sort | Vinay Singh |
| collection | DOAJ |
| description | Psoriasis is a common, chronic, immune mediated, inflammatory disease of skin characterized by red patches enclosed with white scales and affects 2-3% of people in the world. Topical therapy, phototherapy, and systemic therapy were employed for management of disease from many last decades. However, long term uses of these agents are associated with unwanted effects and toxicities. Recently, Itolizumab has been developed as world’s first anti-CD6 humanized monoclonal IgG1 antibody for the management of moderate-to-severe chronic plaque psoriasis in India. Here we are presenting the response indicated by Itolizumab in 7 Indian patients having moderate-to-severe psoriasis with severe comorbidities and who were intolerant/nonresponding to conventional therapies. |
| format | Article |
| id | doaj-art-583237c7403e434dae0017a50c52d185 |
| institution | Kabale University |
| issn | 1687-6105 1687-6113 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Dermatology Research and Practice |
| spelling | doaj-art-583237c7403e434dae0017a50c52d1852025-02-03T05:58:40ZengWileyDermatology Research and Practice1687-61051687-61132016-01-01201610.1155/2016/13163261316326Clinical Outcome of a Novel Anti-CD6 Biologic Itolizumab in Patients of Psoriasis with Comorbid ConditionsVinay Singh0Vibrance Skin Clinic, 412 Pearls Best Height II, Behind Max Hospital, Netaji Subhash Place, Pitampura, Delhi 110034, IndiaPsoriasis is a common, chronic, immune mediated, inflammatory disease of skin characterized by red patches enclosed with white scales and affects 2-3% of people in the world. Topical therapy, phototherapy, and systemic therapy were employed for management of disease from many last decades. However, long term uses of these agents are associated with unwanted effects and toxicities. Recently, Itolizumab has been developed as world’s first anti-CD6 humanized monoclonal IgG1 antibody for the management of moderate-to-severe chronic plaque psoriasis in India. Here we are presenting the response indicated by Itolizumab in 7 Indian patients having moderate-to-severe psoriasis with severe comorbidities and who were intolerant/nonresponding to conventional therapies.http://dx.doi.org/10.1155/2016/1316326 |
| spellingShingle | Vinay Singh Clinical Outcome of a Novel Anti-CD6 Biologic Itolizumab in Patients of Psoriasis with Comorbid Conditions Dermatology Research and Practice |
| title | Clinical Outcome of a Novel Anti-CD6 Biologic Itolizumab in Patients of Psoriasis with Comorbid Conditions |
| title_full | Clinical Outcome of a Novel Anti-CD6 Biologic Itolizumab in Patients of Psoriasis with Comorbid Conditions |
| title_fullStr | Clinical Outcome of a Novel Anti-CD6 Biologic Itolizumab in Patients of Psoriasis with Comorbid Conditions |
| title_full_unstemmed | Clinical Outcome of a Novel Anti-CD6 Biologic Itolizumab in Patients of Psoriasis with Comorbid Conditions |
| title_short | Clinical Outcome of a Novel Anti-CD6 Biologic Itolizumab in Patients of Psoriasis with Comorbid Conditions |
| title_sort | clinical outcome of a novel anti cd6 biologic itolizumab in patients of psoriasis with comorbid conditions |
| url | http://dx.doi.org/10.1155/2016/1316326 |
| work_keys_str_mv | AT vinaysingh clinicaloutcomeofanovelanticd6biologicitolizumabinpatientsofpsoriasiswithcomorbidconditions |