Ultrastructural Study of an Atypical Case of Infertility
An atypical case of infertility associated with severe sperm abnormalities is presented. A 29-year-old man with 4 years of primary infertility had no history of significant illness, and no hereditary pathology or male infertility existed in his family. Physical examination of the patient showed no p...
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| Format: | Article |
| Language: | English |
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Wiley
2007-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2007.151 |
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| author | Ernesto Sánchez Sánchez Carmen Tejedor Mardomingo |
| author_facet | Ernesto Sánchez Sánchez Carmen Tejedor Mardomingo |
| author_sort | Ernesto Sánchez Sánchez |
| collection | DOAJ |
| description | An atypical case of infertility associated with severe sperm abnormalities is presented. A 29-year-old man with 4 years of primary infertility had no history of significant illness, and no hereditary pathology or male infertility existed in his family. Physical examination of the patient showed no pathological findings. The analyses of four semen samples showed: sperm count, 67-83 106/ml; 0% motility. The morphological analysis showed absence of flagellum, 14-16%; short-tail spermatozoa, 45-64%; coiled tails, 12-17%; and an abnormal proportion of spermatids and spermatocytes. Normal spermatozoa were found in 11-16%. Endocrine profile was found within the normal range. Testicular biopsy revealed impaired spermatogenesis. Scanning electron microscopy revealed sperm heads with intact nuclei and acrosomal regions. To our surprise, some of the stunted tails were uniflagellate. To our knowledge, this is a very uncommon case of sperm tail defect. |
| format | Article |
| id | doaj-art-5823af55aa7643059bb6f836203ba156 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2007-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-5823af55aa7643059bb6f836203ba1562025-02-03T01:31:35ZengWileyThe Scientific World Journal1537-744X2007-01-01781882110.1100/tsw.2007.151Ultrastructural Study of an Atypical Case of InfertilityErnesto Sánchez Sánchez0Carmen Tejedor Mardomingo1Department of Urology, University Hospital “Virgen Macarena”, Seville, SpainDepartment of Urology, University Hospital “Virgen Macarena”, Seville, SpainAn atypical case of infertility associated with severe sperm abnormalities is presented. A 29-year-old man with 4 years of primary infertility had no history of significant illness, and no hereditary pathology or male infertility existed in his family. Physical examination of the patient showed no pathological findings. The analyses of four semen samples showed: sperm count, 67-83 106/ml; 0% motility. The morphological analysis showed absence of flagellum, 14-16%; short-tail spermatozoa, 45-64%; coiled tails, 12-17%; and an abnormal proportion of spermatids and spermatocytes. Normal spermatozoa were found in 11-16%. Endocrine profile was found within the normal range. Testicular biopsy revealed impaired spermatogenesis. Scanning electron microscopy revealed sperm heads with intact nuclei and acrosomal regions. To our surprise, some of the stunted tails were uniflagellate. To our knowledge, this is a very uncommon case of sperm tail defect.http://dx.doi.org/10.1100/tsw.2007.151 |
| spellingShingle | Ernesto Sánchez Sánchez Carmen Tejedor Mardomingo Ultrastructural Study of an Atypical Case of Infertility The Scientific World Journal |
| title | Ultrastructural Study of an Atypical Case of Infertility |
| title_full | Ultrastructural Study of an Atypical Case of Infertility |
| title_fullStr | Ultrastructural Study of an Atypical Case of Infertility |
| title_full_unstemmed | Ultrastructural Study of an Atypical Case of Infertility |
| title_short | Ultrastructural Study of an Atypical Case of Infertility |
| title_sort | ultrastructural study of an atypical case of infertility |
| url | http://dx.doi.org/10.1100/tsw.2007.151 |
| work_keys_str_mv | AT ernestosanchezsanchez ultrastructuralstudyofanatypicalcaseofinfertility AT carmentejedormardomingo ultrastructuralstudyofanatypicalcaseofinfertility |