Chemical Composition and Mechanism of Vibriocidal Action of Essential Oil from Resin of Protium heptaphyllum
Protium heptaphyllum is a plant widely distributed in Brazilian ecosystems that produce a resin which has pharmacological activities. In this study, the chemical composition, antimicrobial and antibiofilm activity, and the possible mechanism of action against the bacterium V. parahaemolyticus of ess...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2019/9563213 |
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| author | Josiane Lima Mendes Thiago Ferreira de Araújo Mário Geraldo de Carvalho Francisco Eduardo Aragão Catunda Júnior Renata Albuquerque Costa |
| author_facet | Josiane Lima Mendes Thiago Ferreira de Araújo Mário Geraldo de Carvalho Francisco Eduardo Aragão Catunda Júnior Renata Albuquerque Costa |
| author_sort | Josiane Lima Mendes |
| collection | DOAJ |
| description | Protium heptaphyllum is a plant widely distributed in Brazilian ecosystems that produce a resin which has pharmacological activities. In this study, the chemical composition, antimicrobial and antibiofilm activity, and the possible mechanism of action against the bacterium V. parahaemolyticus of essential oil from P. heptaphyllum (EOPH) were investigated. Twenty-two components were detected in EOPH, and β-phellandrene (60.68%) had the majority. The inhibition halo, MIC, and MBC values were 11 mm, 2 mg/mL, and 8 mg/mL, respectively. Biofilm biomass inhibition and biomass reduction of the preformed biofilm were detected at 4 mg/mL EOPH concentration. The assays of cell constituent release and membrane permeability indicated that EOPH may disrupt the cell membrane, leading to leakage of intracellular constituent as reducing sugars and materials with an absorbance of 260 nm. |
| format | Article |
| id | doaj-art-57b401e8fd814dcf8f67899aadb826b8 |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-57b401e8fd814dcf8f67899aadb826b82025-02-03T01:31:57ZengWileyThe Scientific World Journal2356-61401537-744X2019-01-01201910.1155/2019/95632139563213Chemical Composition and Mechanism of Vibriocidal Action of Essential Oil from Resin of Protium heptaphyllumJosiane Lima Mendes0Thiago Ferreira de Araújo1Mário Geraldo de Carvalho2Francisco Eduardo Aragão Catunda Júnior3Renata Albuquerque Costa4UNINTA College (UNINTA), Sobral, Ceará, BrazilState University of the Tocantina Region of Maranhão, Imperatriz, Maranhão, BrazilChemistry Department, Federal Rural University of Rio de Janeiro, Seropédica, Rio de Janeiro, BrazilState University of the Tocantina Region of Maranhão, Imperatriz, Maranhão, BrazilUNINTA College (UNINTA), Sobral, Ceará, BrazilProtium heptaphyllum is a plant widely distributed in Brazilian ecosystems that produce a resin which has pharmacological activities. In this study, the chemical composition, antimicrobial and antibiofilm activity, and the possible mechanism of action against the bacterium V. parahaemolyticus of essential oil from P. heptaphyllum (EOPH) were investigated. Twenty-two components were detected in EOPH, and β-phellandrene (60.68%) had the majority. The inhibition halo, MIC, and MBC values were 11 mm, 2 mg/mL, and 8 mg/mL, respectively. Biofilm biomass inhibition and biomass reduction of the preformed biofilm were detected at 4 mg/mL EOPH concentration. The assays of cell constituent release and membrane permeability indicated that EOPH may disrupt the cell membrane, leading to leakage of intracellular constituent as reducing sugars and materials with an absorbance of 260 nm.http://dx.doi.org/10.1155/2019/9563213 |
| spellingShingle | Josiane Lima Mendes Thiago Ferreira de Araújo Mário Geraldo de Carvalho Francisco Eduardo Aragão Catunda Júnior Renata Albuquerque Costa Chemical Composition and Mechanism of Vibriocidal Action of Essential Oil from Resin of Protium heptaphyllum The Scientific World Journal |
| title | Chemical Composition and Mechanism of Vibriocidal Action of Essential Oil from Resin of Protium heptaphyllum |
| title_full | Chemical Composition and Mechanism of Vibriocidal Action of Essential Oil from Resin of Protium heptaphyllum |
| title_fullStr | Chemical Composition and Mechanism of Vibriocidal Action of Essential Oil from Resin of Protium heptaphyllum |
| title_full_unstemmed | Chemical Composition and Mechanism of Vibriocidal Action of Essential Oil from Resin of Protium heptaphyllum |
| title_short | Chemical Composition and Mechanism of Vibriocidal Action of Essential Oil from Resin of Protium heptaphyllum |
| title_sort | chemical composition and mechanism of vibriocidal action of essential oil from resin of protium heptaphyllum |
| url | http://dx.doi.org/10.1155/2019/9563213 |
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