Microwave-Assisted, One-Pot Three Component Synthesis of 2-Phenyl H-imidazo[1,2-α]pyridine

A novel synthesis of 2-phenylH-imidazio[1,2-α] pyridines is described from a one-pot, three-component reaction between pyridine, guanidine (urea or thiourea) and α-bromoketones under microwave irradiation and solvent-free conditions in excellent yields.

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Main Authors: Kourosh Motevalli, Zahra Yaghoubi, Roghieh Mirzazadeh
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2012/198615
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author Kourosh Motevalli
Zahra Yaghoubi
Roghieh Mirzazadeh
author_facet Kourosh Motevalli
Zahra Yaghoubi
Roghieh Mirzazadeh
author_sort Kourosh Motevalli
collection DOAJ
description A novel synthesis of 2-phenylH-imidazio[1,2-α] pyridines is described from a one-pot, three-component reaction between pyridine, guanidine (urea or thiourea) and α-bromoketones under microwave irradiation and solvent-free conditions in excellent yields.
format Article
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institution Kabale University
issn 0973-4945
2090-9810
language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series E-Journal of Chemistry
spelling doaj-art-579d96f358494ff0a6c1f2d6054db0bf2025-02-03T05:58:40ZengWileyE-Journal of Chemistry0973-49452090-98102012-01-01931047105210.1155/2012/198615Microwave-Assisted, One-Pot Three Component Synthesis of 2-Phenyl H-imidazo[1,2-α]pyridineKourosh Motevalli0Zahra Yaghoubi1Roghieh Mirzazadeh2Department of Applied Chemistry, Islamic Azad University, Tehran South Branch, Tehran, IranIndustrial faculty, Islamic Azad University, Tehran South Branch, Tehran, IranDepartment of Biochemistry, Pasteur Institute of Iran, Tehran, IranA novel synthesis of 2-phenylH-imidazio[1,2-α] pyridines is described from a one-pot, three-component reaction between pyridine, guanidine (urea or thiourea) and α-bromoketones under microwave irradiation and solvent-free conditions in excellent yields.http://dx.doi.org/10.1155/2012/198615
spellingShingle Kourosh Motevalli
Zahra Yaghoubi
Roghieh Mirzazadeh
Microwave-Assisted, One-Pot Three Component Synthesis of 2-Phenyl H-imidazo[1,2-α]pyridine
E-Journal of Chemistry
title Microwave-Assisted, One-Pot Three Component Synthesis of 2-Phenyl H-imidazo[1,2-α]pyridine
title_full Microwave-Assisted, One-Pot Three Component Synthesis of 2-Phenyl H-imidazo[1,2-α]pyridine
title_fullStr Microwave-Assisted, One-Pot Three Component Synthesis of 2-Phenyl H-imidazo[1,2-α]pyridine
title_full_unstemmed Microwave-Assisted, One-Pot Three Component Synthesis of 2-Phenyl H-imidazo[1,2-α]pyridine
title_short Microwave-Assisted, One-Pot Three Component Synthesis of 2-Phenyl H-imidazo[1,2-α]pyridine
title_sort microwave assisted one pot three component synthesis of 2 phenyl h imidazo 1 2 α pyridine
url http://dx.doi.org/10.1155/2012/198615
work_keys_str_mv AT kouroshmotevalli microwaveassistedonepotthreecomponentsynthesisof2phenylhimidazo12apyridine
AT zahrayaghoubi microwaveassistedonepotthreecomponentsynthesisof2phenylhimidazo12apyridine
AT roghiehmirzazadeh microwaveassistedonepotthreecomponentsynthesisof2phenylhimidazo12apyridine