How a gene fuels ear infections
The DYRK1A enzyme is a pivotal contributor to frequent and severe episodes of otitis media in Down syndrome, positioning it as a promising target for therapeutic interventions.
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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eLife Sciences Publications Ltd
2025-01-01
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| Series: | eLife |
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| Online Access: | https://elifesciences.org/articles/105612 |
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| _version_ | 1832591439529246720 |
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| author | Sedigheh Delmaghani Aziz El-Amraoui |
| author_facet | Sedigheh Delmaghani Aziz El-Amraoui |
| author_sort | Sedigheh Delmaghani |
| collection | DOAJ |
| description | The DYRK1A enzyme is a pivotal contributor to frequent and severe episodes of otitis media in Down syndrome, positioning it as a promising target for therapeutic interventions. |
| format | Article |
| id | doaj-art-579cad12304d4ccaa30eb8727e23257d |
| institution | Kabale University |
| issn | 2050-084X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| series | eLife |
| spelling | doaj-art-579cad12304d4ccaa30eb8727e23257d2025-01-22T11:00:19ZengeLife Sciences Publications LtdeLife2050-084X2025-01-011410.7554/eLife.105612How a gene fuels ear infectionsSedigheh Delmaghani0https://orcid.org/0000-0003-2092-5097Aziz El-Amraoui1https://orcid.org/0000-0003-2692-4984Université Paris Cité, Institut Pasteur, AP-HP, Inserm, CNRS, Fondation Pour l'Audition, Institut de l’Audition, IHU reconnect, Progressive Sensory Disorders, Pathophysiology and Therapy Unit, Paris, FranceUniversité Paris Cité, Institut Pasteur, AP-HP, Inserm, CNRS, Fondation Pour l'Audition, Institut de l’Audition, IHU reconnect, Progressive Sensory Disorders, Pathophysiology and Therapy Unit, Paris, FranceThe DYRK1A enzyme is a pivotal contributor to frequent and severe episodes of otitis media in Down syndrome, positioning it as a promising target for therapeutic interventions.https://elifesciences.org/articles/105612down syndromeotitis mediaDYRK1Ainflammationhearing lossMiddle ear |
| spellingShingle | Sedigheh Delmaghani Aziz El-Amraoui How a gene fuels ear infections eLife down syndrome otitis media DYRK1A inflammation hearing loss Middle ear |
| title | How a gene fuels ear infections |
| title_full | How a gene fuels ear infections |
| title_fullStr | How a gene fuels ear infections |
| title_full_unstemmed | How a gene fuels ear infections |
| title_short | How a gene fuels ear infections |
| title_sort | how a gene fuels ear infections |
| topic | down syndrome otitis media DYRK1A inflammation hearing loss Middle ear |
| url | https://elifesciences.org/articles/105612 |
| work_keys_str_mv | AT sedighehdelmaghani howagenefuelsearinfections AT azizelamraoui howagenefuelsearinfections |