Nutritional Status and Immune Functions in Maintenance Hemodialysis Patients
Epidemiological studies suggest various kinds of immune dysregulation in hemodialysis (HD) patients. The aim of this study was to investigate the relationship between immune functions and nutritional status of HD patients. We studied 54 patients with ESRD on chronic HD, included 34 females and 20 ma...
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Format: | Article |
Language: | English |
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Wiley
2006-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/MI/2006/20264 |
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author | Hayriye Sayarlioglu Reha Erkoc Cengiz Demir Ekrem Dogan Mehmet Sayarlioglu Ahmet Faik Oner Imdat Dilek |
author_facet | Hayriye Sayarlioglu Reha Erkoc Cengiz Demir Ekrem Dogan Mehmet Sayarlioglu Ahmet Faik Oner Imdat Dilek |
author_sort | Hayriye Sayarlioglu |
collection | DOAJ |
description | Epidemiological studies suggest various kinds of immune
dysregulation in hemodialysis (HD) patients. The aim of this study
was to investigate the relationship between immune functions and
nutritional status of HD patients. We studied 54 patients with
ESRD on chronic HD, included 34 females and 20 males with mean
age 46.6±16.3 (18–77) years.
We measured the height and dry
weight of all patients. The BMI was calculated by dividing weight
(kg) by height squared (m2). In all patients serum urea,
creatinine, albumin, iron, cholesterol, triglyceride, CRP, IgG,
IgM, IgA, CD4, CD8, CD19, CD16-56 lymphocytes were measured. Kt/V
values were calculated according to DOQI guideline. In this study,
a positive correlation between albumin, cholesterol, and
triglyceride levels as nutritional parameters and immune functions
in terms of total and subtype lymphocyte counts was
observed. Further prospective studies are needed to determine the
clinical importance of this finding and the appropriate means of
measurement and effects of nutrition on immune function in
hemodialysis patients. |
format | Article |
id | doaj-art-579003ebee4141fda997bcbb2d027ec8 |
institution | Kabale University |
issn | 0962-9351 1466-1861 |
language | English |
publishDate | 2006-01-01 |
publisher | Wiley |
record_format | Article |
series | Mediators of Inflammation |
spelling | doaj-art-579003ebee4141fda997bcbb2d027ec82025-02-03T01:31:47ZengWileyMediators of Inflammation0962-93511466-18612006-01-01200610.1155/MI/2006/2026420264Nutritional Status and Immune Functions in Maintenance Hemodialysis PatientsHayriye Sayarlioglu0Reha Erkoc1Cengiz Demir2Ekrem Dogan3Mehmet Sayarlioglu4Ahmet Faik Oner5Imdat Dilek6Division of Nephrology, Department of Internal Medicine, Medical Faculty, Yuzuncu Yil University, Van 65200, TurkeyDivision of Nephrology, Department of Internal Medicine, Medical Faculty, Yuzuncu Yil University, Van 65200, TurkeyDivision of Hematology, Department of Internal Medicine, Medical Faculty, Yuzuncu Yil University, Van 65200, TurkeyDivision of Nephrology, Department of Internal Medicine, Medical Faculty, Yuzuncu Yil University, Van 65200, TurkeyDivision of Nephrology, Department of Internal Medicine, Medical Faculty, Yuzuncu Yil University, Van 65200, TurkeyDivision of Hematology, Department of Internal Medicine, Medical Faculty, Yuzuncu Yil University, Van 65200, TurkeyDivision of Hematology, Department of Internal Medicine, Medical Faculty, Yuzuncu Yil University, Van 65200, TurkeyEpidemiological studies suggest various kinds of immune dysregulation in hemodialysis (HD) patients. The aim of this study was to investigate the relationship between immune functions and nutritional status of HD patients. We studied 54 patients with ESRD on chronic HD, included 34 females and 20 males with mean age 46.6±16.3 (18–77) years. We measured the height and dry weight of all patients. The BMI was calculated by dividing weight (kg) by height squared (m2). In all patients serum urea, creatinine, albumin, iron, cholesterol, triglyceride, CRP, IgG, IgM, IgA, CD4, CD8, CD19, CD16-56 lymphocytes were measured. Kt/V values were calculated according to DOQI guideline. In this study, a positive correlation between albumin, cholesterol, and triglyceride levels as nutritional parameters and immune functions in terms of total and subtype lymphocyte counts was observed. Further prospective studies are needed to determine the clinical importance of this finding and the appropriate means of measurement and effects of nutrition on immune function in hemodialysis patients.http://dx.doi.org/10.1155/MI/2006/20264 |
spellingShingle | Hayriye Sayarlioglu Reha Erkoc Cengiz Demir Ekrem Dogan Mehmet Sayarlioglu Ahmet Faik Oner Imdat Dilek Nutritional Status and Immune Functions in Maintenance Hemodialysis Patients Mediators of Inflammation |
title | Nutritional Status and Immune Functions in Maintenance Hemodialysis Patients |
title_full | Nutritional Status and Immune Functions in Maintenance Hemodialysis Patients |
title_fullStr | Nutritional Status and Immune Functions in Maintenance Hemodialysis Patients |
title_full_unstemmed | Nutritional Status and Immune Functions in Maintenance Hemodialysis Patients |
title_short | Nutritional Status and Immune Functions in Maintenance Hemodialysis Patients |
title_sort | nutritional status and immune functions in maintenance hemodialysis patients |
url | http://dx.doi.org/10.1155/MI/2006/20264 |
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