Is There an Ideal Concentration of Ozonized Oil for the Prevention and Modulation of Zoledronate-Induced Mandibular Osteonecrosis? A Study on Senescent Rats

Is There an Ideal Concentration of Ozonized Oil for the Prevention and Modulation of Zoledronate-Induced Mandibular Osteonecrosis? A Study on Senescent Rats

This study aimed to identify whether there is an ideal concentration for applying ozonized oil (OZ) in the post-exodontic alveoli of senescent rats treated with zoledronate (ZOL). Thirty-five female rats, aged 18 months, were divided into five groups: ZOL; ZOL+OZ500; ZOL+OZ600; ZOL+OZ700; and SAL. T...

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Bibliographic Details
Main Authors: Mirela Caroline Silva, Izabela Fornazari Delamura, Maria Eloise de Sá Simon, Stefany Barbosa, David Tawei Ting, Karen Bechara, Jamil Awad Shibli, Carlos Fernando Mourão, Ana Paula Farnezi Bassi, Edilson Ervolino, Leonardo Perez Faverani
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Journal of Functional Biomaterials
Subjects:
ozone
osteonecrosis
osteonecrosis associated with bisphosphonates
healing
Online Access:https://www.mdpi.com/2079-4983/15/12/353
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