Morphologic Heterogeneity in Carcinosarcoma of the Gallbladder: Report of a Rare Cases

Carcinosarcoma is a rare tumor composed of variable proportions of carcinomatous and sarcomatous elements and comprises less than one percent of all gallbladder malignancies. In most reported cases of carcinosarcoma of gallbladder, the epithelial component is adenocarcinoma. The mesenchymal componen...

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Main Authors: Vani Krishnamurthy, Sheela Devi C. Shivalingiah, Sunila Ravishankar, Gubbanna V. Manjunath
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2011/929654
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author Vani Krishnamurthy
Sheela Devi C. Shivalingiah
Sunila Ravishankar
Gubbanna V. Manjunath
author_facet Vani Krishnamurthy
Sheela Devi C. Shivalingiah
Sunila Ravishankar
Gubbanna V. Manjunath
author_sort Vani Krishnamurthy
collection DOAJ
description Carcinosarcoma is a rare tumor composed of variable proportions of carcinomatous and sarcomatous elements and comprises less than one percent of all gallbladder malignancies. In most reported cases of carcinosarcoma of gallbladder, the epithelial component is adenocarcinoma. The mesenchymal component varies from homogenous sarcoma to more heterotopic elements like malignant bone, cartilage, and other mesenchymal tissues. We report a rare case of carcinosarcoma of the gallbladder in an 83-year-old male, with the carcinomatous component represented by undifferentiated carcinoma (spindle and giant cell type with osteoclastic giant cells) and the mesenchymal component seen as foci of chondrosarcoma.
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institution Kabale University
issn 2090-6781
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publishDate 2011-01-01
publisher Wiley
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series Case Reports in Pathology
spelling doaj-art-577c06efb3634befa40737fe29ed77802025-02-03T01:23:31ZengWileyCase Reports in Pathology2090-67812090-679X2011-01-01201110.1155/2011/929654929654Morphologic Heterogeneity in Carcinosarcoma of the Gallbladder: Report of a Rare CasesVani Krishnamurthy0Sheela Devi C. Shivalingiah1Sunila Ravishankar2Gubbanna V. Manjunath3Department of Pathology, JSS Hospital, MG Road, Mysore, Karnataka 570004, IndiaDepartment of Pathology, JSS Hospital, MG Road, Mysore, Karnataka 570004, IndiaDepartment of Pathology, JSS Hospital, MG Road, Mysore, Karnataka 570004, IndiaDepartment of Pathology, JSS Hospital, MG Road, Mysore, Karnataka 570004, IndiaCarcinosarcoma is a rare tumor composed of variable proportions of carcinomatous and sarcomatous elements and comprises less than one percent of all gallbladder malignancies. In most reported cases of carcinosarcoma of gallbladder, the epithelial component is adenocarcinoma. The mesenchymal component varies from homogenous sarcoma to more heterotopic elements like malignant bone, cartilage, and other mesenchymal tissues. We report a rare case of carcinosarcoma of the gallbladder in an 83-year-old male, with the carcinomatous component represented by undifferentiated carcinoma (spindle and giant cell type with osteoclastic giant cells) and the mesenchymal component seen as foci of chondrosarcoma.http://dx.doi.org/10.1155/2011/929654
spellingShingle Vani Krishnamurthy
Sheela Devi C. Shivalingiah
Sunila Ravishankar
Gubbanna V. Manjunath
Morphologic Heterogeneity in Carcinosarcoma of the Gallbladder: Report of a Rare Cases
Case Reports in Pathology
title Morphologic Heterogeneity in Carcinosarcoma of the Gallbladder: Report of a Rare Cases
title_full Morphologic Heterogeneity in Carcinosarcoma of the Gallbladder: Report of a Rare Cases
title_fullStr Morphologic Heterogeneity in Carcinosarcoma of the Gallbladder: Report of a Rare Cases
title_full_unstemmed Morphologic Heterogeneity in Carcinosarcoma of the Gallbladder: Report of a Rare Cases
title_short Morphologic Heterogeneity in Carcinosarcoma of the Gallbladder: Report of a Rare Cases
title_sort morphologic heterogeneity in carcinosarcoma of the gallbladder report of a rare cases
url http://dx.doi.org/10.1155/2011/929654
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AT sunilaravishankar morphologicheterogeneityincarcinosarcomaofthegallbladderreportofararecases
AT gubbannavmanjunath morphologicheterogeneityincarcinosarcomaofthegallbladderreportofararecases