Epstein-Barr Virus Encephalitis in an Immunocompetent Child: A Case Report and Management of Epstein-Barr Virus Encephalitis
Epstein-Barr virus (EBV) usually causes mild, asymptomatic, and self-limited infections in children and adults; however, it may occasionally lead to severe conditions such as neurological diseases, malignant diseases, hepatic failure, and myocarditis. Epstein-Barr virus-related neurological disorder...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2016/7549252 |
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| author | Gulsen Akkoc Eda Kepenekli Kadayifci Ayse Karaaslan Serkan Atici Nurhayat Yakut Sevliya Ocal Demir Ahmet Soysal Mustafa Bakir |
| author_facet | Gulsen Akkoc Eda Kepenekli Kadayifci Ayse Karaaslan Serkan Atici Nurhayat Yakut Sevliya Ocal Demir Ahmet Soysal Mustafa Bakir |
| author_sort | Gulsen Akkoc |
| collection | DOAJ |
| description | Epstein-Barr virus (EBV) usually causes mild, asymptomatic, and self-limited infections in children and adults; however, it may occasionally lead to severe conditions such as neurological diseases, malignant diseases, hepatic failure, and myocarditis. Epstein-Barr virus-related neurological disorders include meningitis, encephalitis, and cranial or peripheral neuritis, which are mostly seen in immunocompromised patients. The therapeutic modalities for EBV-related severe organ damage including central nervous system manifestations are still uncertain. Herein, we describe a seven-year-old boy with EBV encephalitis who presented with prolonged fever, exudative pharyngitis, reduced consciousness, and neck stiffness. Cranial magnetic resonance imaging showed contrast enhancement in the bilateral insular cortex and the right hypothalamus. The diagnosis was made by EBV-DNA amplification in both the blood and cerebrospinal fluid samples. He was discharged with acyclovir therapy without any sequelae. |
| format | Article |
| id | doaj-art-577ac6c099014bd186c0cddf7e4346f0 |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-577ac6c099014bd186c0cddf7e4346f02025-02-03T05:47:01ZengWileyCase Reports in Infectious Diseases2090-66252090-66332016-01-01201610.1155/2016/75492527549252Epstein-Barr Virus Encephalitis in an Immunocompetent Child: A Case Report and Management of Epstein-Barr Virus EncephalitisGulsen Akkoc0Eda Kepenekli Kadayifci1Ayse Karaaslan2Serkan Atici3Nurhayat Yakut4Sevliya Ocal Demir5Ahmet Soysal6Mustafa Bakir7Division of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University School of Medicine, 34890 Istanbul, TurkeyDivision of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University School of Medicine, 34890 Istanbul, TurkeyDivision of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University School of Medicine, 34890 Istanbul, TurkeyDivision of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University School of Medicine, 34890 Istanbul, TurkeyDivision of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University School of Medicine, 34890 Istanbul, TurkeyDivision of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University School of Medicine, 34890 Istanbul, TurkeyDivision of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University School of Medicine, 34890 Istanbul, TurkeyDivision of Pediatric Infectious Diseases, Department of Pediatrics, Marmara University School of Medicine, 34890 Istanbul, TurkeyEpstein-Barr virus (EBV) usually causes mild, asymptomatic, and self-limited infections in children and adults; however, it may occasionally lead to severe conditions such as neurological diseases, malignant diseases, hepatic failure, and myocarditis. Epstein-Barr virus-related neurological disorders include meningitis, encephalitis, and cranial or peripheral neuritis, which are mostly seen in immunocompromised patients. The therapeutic modalities for EBV-related severe organ damage including central nervous system manifestations are still uncertain. Herein, we describe a seven-year-old boy with EBV encephalitis who presented with prolonged fever, exudative pharyngitis, reduced consciousness, and neck stiffness. Cranial magnetic resonance imaging showed contrast enhancement in the bilateral insular cortex and the right hypothalamus. The diagnosis was made by EBV-DNA amplification in both the blood and cerebrospinal fluid samples. He was discharged with acyclovir therapy without any sequelae.http://dx.doi.org/10.1155/2016/7549252 |
| spellingShingle | Gulsen Akkoc Eda Kepenekli Kadayifci Ayse Karaaslan Serkan Atici Nurhayat Yakut Sevliya Ocal Demir Ahmet Soysal Mustafa Bakir Epstein-Barr Virus Encephalitis in an Immunocompetent Child: A Case Report and Management of Epstein-Barr Virus Encephalitis Case Reports in Infectious Diseases |
| title | Epstein-Barr Virus Encephalitis in an Immunocompetent Child: A Case Report and Management of Epstein-Barr Virus Encephalitis |
| title_full | Epstein-Barr Virus Encephalitis in an Immunocompetent Child: A Case Report and Management of Epstein-Barr Virus Encephalitis |
| title_fullStr | Epstein-Barr Virus Encephalitis in an Immunocompetent Child: A Case Report and Management of Epstein-Barr Virus Encephalitis |
| title_full_unstemmed | Epstein-Barr Virus Encephalitis in an Immunocompetent Child: A Case Report and Management of Epstein-Barr Virus Encephalitis |
| title_short | Epstein-Barr Virus Encephalitis in an Immunocompetent Child: A Case Report and Management of Epstein-Barr Virus Encephalitis |
| title_sort | epstein barr virus encephalitis in an immunocompetent child a case report and management of epstein barr virus encephalitis |
| url | http://dx.doi.org/10.1155/2016/7549252 |
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