Efektivitas Penggunaan Platelet-Rich Plasma (PRP) dalam Proses Penyembuhan Tulang pada Model Hewan Coba: Systematic Review

Bone injury causes thus, reduced productivity and death in the sufferer. Alternative treatment research was developed to speed up the bone healing process, including autologous treatments such as Platelet-Rich Plasma (PRP). Objective: To assessed the effectiveness of PRP use in the bone healing proc...

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Main Authors: Noverial Noverial, Biomechy Oktomalio Putri
Format: Article
Language:English
Published: Faculty of Medicine at Universitas Andalas 2023-04-01
Series:Jurnal Kesehatan Andalas
Online Access:http://jurnal.fk.unand.ac.id/index.php/jka/article/view/2129
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author Noverial Noverial
Biomechy Oktomalio Putri
author_facet Noverial Noverial
Biomechy Oktomalio Putri
author_sort Noverial Noverial
collection DOAJ
description Bone injury causes thus, reduced productivity and death in the sufferer. Alternative treatment research was developed to speed up the bone healing process, including autologous treatments such as Platelet-Rich Plasma (PRP). Objective: To assessed the effectiveness of PRP use in the bone healing process on studies with experimental animal models. Methods: This study was a systematic review research whose article searches through the databases such as PubMed, ScienceDirect and ProQuest on English-language articles published from 2012-2022. The keywords used were ((bone healing OR fracture healing OR bone defect) AND (platelet rich plasma OR prp) AND (animal models)). Results: PRP was effective in accelerating bone regeneration in every experimental animal model in the early phases of healing, but not all studies have significant differences between groups that used PRP and those who did not. Conclusion: PRP has a positive impact in increasing bone mineral density, but the effectiveness of using PRP may vary from study result to study result, depending on the characteristics of the experimental animal model used in the study and the accuracy of concentration in the administration of PRP. Keywords: animal models, bone healing, platelet-rich plasma
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institution Kabale University
issn 2301-7406
2615-1138
language English
publishDate 2023-04-01
publisher Faculty of Medicine at Universitas Andalas
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series Jurnal Kesehatan Andalas
spelling doaj-art-5775dd778e734daab5544fa73d0a7c132025-02-03T03:39:38ZengFaculty of Medicine at Universitas AndalasJurnal Kesehatan Andalas2301-74062615-11382023-04-0111318419010.25077/jka.v11i3.21291233Efektivitas Penggunaan Platelet-Rich Plasma (PRP) dalam Proses Penyembuhan Tulang pada Model Hewan Coba: Systematic ReviewNoverial Noverial0Biomechy Oktomalio Putri1Faculty of Medicine, Universitas Andalas, PadangFaculty of Medicine, Universitas Andalas, PadangBone injury causes thus, reduced productivity and death in the sufferer. Alternative treatment research was developed to speed up the bone healing process, including autologous treatments such as Platelet-Rich Plasma (PRP). Objective: To assessed the effectiveness of PRP use in the bone healing process on studies with experimental animal models. Methods: This study was a systematic review research whose article searches through the databases such as PubMed, ScienceDirect and ProQuest on English-language articles published from 2012-2022. The keywords used were ((bone healing OR fracture healing OR bone defect) AND (platelet rich plasma OR prp) AND (animal models)). Results: PRP was effective in accelerating bone regeneration in every experimental animal model in the early phases of healing, but not all studies have significant differences between groups that used PRP and those who did not. Conclusion: PRP has a positive impact in increasing bone mineral density, but the effectiveness of using PRP may vary from study result to study result, depending on the characteristics of the experimental animal model used in the study and the accuracy of concentration in the administration of PRP. Keywords: animal models, bone healing, platelet-rich plasmahttp://jurnal.fk.unand.ac.id/index.php/jka/article/view/2129
spellingShingle Noverial Noverial
Biomechy Oktomalio Putri
Efektivitas Penggunaan Platelet-Rich Plasma (PRP) dalam Proses Penyembuhan Tulang pada Model Hewan Coba: Systematic Review
Jurnal Kesehatan Andalas
title Efektivitas Penggunaan Platelet-Rich Plasma (PRP) dalam Proses Penyembuhan Tulang pada Model Hewan Coba: Systematic Review
title_full Efektivitas Penggunaan Platelet-Rich Plasma (PRP) dalam Proses Penyembuhan Tulang pada Model Hewan Coba: Systematic Review
title_fullStr Efektivitas Penggunaan Platelet-Rich Plasma (PRP) dalam Proses Penyembuhan Tulang pada Model Hewan Coba: Systematic Review
title_full_unstemmed Efektivitas Penggunaan Platelet-Rich Plasma (PRP) dalam Proses Penyembuhan Tulang pada Model Hewan Coba: Systematic Review
title_short Efektivitas Penggunaan Platelet-Rich Plasma (PRP) dalam Proses Penyembuhan Tulang pada Model Hewan Coba: Systematic Review
title_sort efektivitas penggunaan platelet rich plasma prp dalam proses penyembuhan tulang pada model hewan coba systematic review
url http://jurnal.fk.unand.ac.id/index.php/jka/article/view/2129
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