Sample size estimation for task-related functional MRI studies using Bayesian updating
Task-related functional MRI (fMRI) studies need to be properly powered with an adequate sample size to reliably detect effects of interest. But for most fMRI studies, it is not straightforward to determine a proper sample size using power calculations based on published effect sizes. Here, we presen...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Developmental Cognitive Neuroscience |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878929324001506 |
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| author | Eduard T. Klapwijk Joran Jongerling Herbert Hoijtink Eveline A. Crone |
| author_facet | Eduard T. Klapwijk Joran Jongerling Herbert Hoijtink Eveline A. Crone |
| author_sort | Eduard T. Klapwijk |
| collection | DOAJ |
| description | Task-related functional MRI (fMRI) studies need to be properly powered with an adequate sample size to reliably detect effects of interest. But for most fMRI studies, it is not straightforward to determine a proper sample size using power calculations based on published effect sizes. Here, we present an alternative approach of sample size estimation with empirical Bayesian updating. First, this method provides an estimate of the required sample size using existing data from a similar task and similar region of interest. Using this estimate researchers can plan their research project, and report empirically determined sample size estimations in their research proposal or pre-registration. Second, researchers can expand the sample size estimations with new data. We illustrate this approach using four existing fMRI data sets where Cohen’s d is the effect size of interest for the hemodynamic response in the task condition of interest versus a control condition, and where a Pearson correlation between task effect and age is the covariate of interest. We show that sample sizes to reliably detect effects differ between various tasks and regions of interest. We provide an R package to allow researchers to use Bayesian updating with other task-related fMRI studies. |
| format | Article |
| id | doaj-art-576f350e9a874032a52d311a50722808 |
| institution | Kabale University |
| issn | 1878-9293 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Developmental Cognitive Neuroscience |
| spelling | doaj-art-576f350e9a874032a52d311a507228082025-01-22T05:41:17ZengElsevierDevelopmental Cognitive Neuroscience1878-92932025-01-0171101489Sample size estimation for task-related functional MRI studies using Bayesian updatingEduard T. Klapwijk0Joran Jongerling1Herbert Hoijtink2Eveline A. Crone3Erasmus University Rotterdam, Netherlands; Corresponding author.Tilburg University, NetherlandsUtrecht University, NetherlandsErasmus University Rotterdam, Netherlands; Leiden University, NetherlandsTask-related functional MRI (fMRI) studies need to be properly powered with an adequate sample size to reliably detect effects of interest. But for most fMRI studies, it is not straightforward to determine a proper sample size using power calculations based on published effect sizes. Here, we present an alternative approach of sample size estimation with empirical Bayesian updating. First, this method provides an estimate of the required sample size using existing data from a similar task and similar region of interest. Using this estimate researchers can plan their research project, and report empirically determined sample size estimations in their research proposal or pre-registration. Second, researchers can expand the sample size estimations with new data. We illustrate this approach using four existing fMRI data sets where Cohen’s d is the effect size of interest for the hemodynamic response in the task condition of interest versus a control condition, and where a Pearson correlation between task effect and age is the covariate of interest. We show that sample sizes to reliably detect effects differ between various tasks and regions of interest. We provide an R package to allow researchers to use Bayesian updating with other task-related fMRI studies.http://www.sciencedirect.com/science/article/pii/S1878929324001506Power analysisRegion of interestEffect sizeR packageSample sizesBayesian updating |
| spellingShingle | Eduard T. Klapwijk Joran Jongerling Herbert Hoijtink Eveline A. Crone Sample size estimation for task-related functional MRI studies using Bayesian updating Developmental Cognitive Neuroscience Power analysis Region of interest Effect size R package Sample sizes Bayesian updating |
| title | Sample size estimation for task-related functional MRI studies using Bayesian updating |
| title_full | Sample size estimation for task-related functional MRI studies using Bayesian updating |
| title_fullStr | Sample size estimation for task-related functional MRI studies using Bayesian updating |
| title_full_unstemmed | Sample size estimation for task-related functional MRI studies using Bayesian updating |
| title_short | Sample size estimation for task-related functional MRI studies using Bayesian updating |
| title_sort | sample size estimation for task related functional mri studies using bayesian updating |
| topic | Power analysis Region of interest Effect size R package Sample sizes Bayesian updating |
| url | http://www.sciencedirect.com/science/article/pii/S1878929324001506 |
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