Synergistic effect of blocking cancer cell invasionrevealed by computer simulations
Invasion and metastasis are the main cause of death in cancer patients. The initial step of invasion is the degradation of extracellular matrix (ECM) by primary cancer cells in a tissue. Membranous metalloproteinase MT1-MMP and soluble metalloproteinase MMP-2 are thought to play an important role in...
Saved in:
Main Author: | Kazuhisa Ichikawa |
---|---|
Format: | Article |
Language: | English |
Published: |
AIMS Press
2015-07-01
|
Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2015.12.1189 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Targeting Invasion: The Role of MMP-2 and MMP-9 Inhibition in Colorectal Cancer Therapy
by: Alireza Shoari, et al.
Published: (2024-12-01) -
T Cell Control of Extracellular Matrix Degradation
by: Yves St-Pierre, et al.
Published: (2000-01-01) -
Mebendazole Exerts Anticancer Activity in Ovarian Cancer Cell Lines via Novel Girdin-Mediated AKT/IKKα/β/NF-κB Signaling Axis
by: Rahul Gupta, et al.
Published: (2025-01-01) -
Expression and correlation of endoglin, sEndoglin, and MMP-14 on preeclampsia placenta
by: Febriana Catur Iswanti, et al.
Published: (2024-11-01) -
Predictive value of MMP-2, MMP-9, TIMP-1 in surgical treatment of localized renal cell cancer
by: A. I. Tarasenko, et al.
Published: (2021-06-01)