Synergistic effect of blocking cancer cell invasionrevealed by computer simulations

Invasion and metastasis are the main cause of death in cancer patients. The initial step of invasion is the degradation of extracellular matrix (ECM) by primary cancer cells in a tissue. Membranous metalloproteinase MT1-MMP and soluble metalloproteinase MMP-2 are thought to play an important role in...

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Bibliographic Details
Main Author: Kazuhisa Ichikawa
Format: Article
Language:English
Published: AIMS Press 2015-07-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2015.12.1189
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