Gestational Medication Use, Birth Conditions, and Early Postnatal Exposures for Childhood Asthma
Our aim is to explore (1) whether gestational medication use, mode of delivery, and early postnatal exposure correlate with childhood asthma, (2) the dose responsiveness of such exposure, and (3) their links to early- and late-onset asthma. We conducted a matched case-control study based on the Taiw...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Clinical and Developmental Immunology |
| Online Access: | http://dx.doi.org/10.1155/2012/913426 |
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| author | Yang-Ching Chen Ching-Hui Tsai Yungling Lee |
| author_facet | Yang-Ching Chen Ching-Hui Tsai Yungling Lee |
| author_sort | Yang-Ching Chen |
| collection | DOAJ |
| description | Our aim is to explore (1) whether gestational medication use, mode of delivery, and early postnatal exposure correlate with childhood asthma, (2) the dose responsiveness of such exposure, and (3) their links to early- and late-onset asthma. We conducted a matched case-control study based on the Taiwan Children Health Study, which was a nationwide survey that recruited 12-to-14-year-old school children in 14 communities. 579 mothers of the participants were interviewed by telephone. Exclusive breastfeeding protected children from asthma. Notably, childhood asthma was significantly associated with maternal medication use during pregnancy, vacuum use during vaginal delivery, recurrent respiratory tract infections, hospitalization, main caregiver cared for other children, and early daycare attendance. Exposure to these factors led to dose responsiveness in relationships to asthma. Most of the exposures revealed a greater impact on early-onset asthma, except for vacuum use and daycare attendance. |
| format | Article |
| id | doaj-art-575b6fb032bc4f3991b4b0ae5b7835dd |
| institution | Kabale University |
| issn | 1740-2522 1740-2530 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical and Developmental Immunology |
| spelling | doaj-art-575b6fb032bc4f3991b4b0ae5b7835dd2025-02-03T05:44:54ZengWileyClinical and Developmental Immunology1740-25221740-25302012-01-01201210.1155/2012/913426913426Gestational Medication Use, Birth Conditions, and Early Postnatal Exposures for Childhood AsthmaYang-Ching Chen0Ching-Hui Tsai1Yungling Lee2Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei 100, TaiwanInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei 100, TaiwanInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei 100, TaiwanOur aim is to explore (1) whether gestational medication use, mode of delivery, and early postnatal exposure correlate with childhood asthma, (2) the dose responsiveness of such exposure, and (3) their links to early- and late-onset asthma. We conducted a matched case-control study based on the Taiwan Children Health Study, which was a nationwide survey that recruited 12-to-14-year-old school children in 14 communities. 579 mothers of the participants were interviewed by telephone. Exclusive breastfeeding protected children from asthma. Notably, childhood asthma was significantly associated with maternal medication use during pregnancy, vacuum use during vaginal delivery, recurrent respiratory tract infections, hospitalization, main caregiver cared for other children, and early daycare attendance. Exposure to these factors led to dose responsiveness in relationships to asthma. Most of the exposures revealed a greater impact on early-onset asthma, except for vacuum use and daycare attendance.http://dx.doi.org/10.1155/2012/913426 |
| spellingShingle | Yang-Ching Chen Ching-Hui Tsai Yungling Lee Gestational Medication Use, Birth Conditions, and Early Postnatal Exposures for Childhood Asthma Clinical and Developmental Immunology |
| title | Gestational Medication Use, Birth Conditions, and Early Postnatal Exposures for Childhood Asthma |
| title_full | Gestational Medication Use, Birth Conditions, and Early Postnatal Exposures for Childhood Asthma |
| title_fullStr | Gestational Medication Use, Birth Conditions, and Early Postnatal Exposures for Childhood Asthma |
| title_full_unstemmed | Gestational Medication Use, Birth Conditions, and Early Postnatal Exposures for Childhood Asthma |
| title_short | Gestational Medication Use, Birth Conditions, and Early Postnatal Exposures for Childhood Asthma |
| title_sort | gestational medication use birth conditions and early postnatal exposures for childhood asthma |
| url | http://dx.doi.org/10.1155/2012/913426 |
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