A case report of an early neonatal death accompanied by disseminated intravascular coagulation caused by severe acute respiratory syndrome Coronavirus-2 infection
Introduction: Women with coronavirus disease 2019 (COVID-19) during pregnancy are more likely to develop a severe form of the disease and have unfavorable pregnancy outcomes. Case report: We report the case of a 21-year-old woman diagnosed with disseminated intravascular coagulation (DIC) caused by...
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| Language: | English |
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Srpsko lekarsko drustvo
2024-01-01
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| Series: | Hospital Pharmacology |
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| Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/2334-9492/2024/2334-94922403469M.pdf |
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| author | Mitić Gorana P. Spasić Igor G. Panjković Milana D. Vučković Biljana A. |
| author_facet | Mitić Gorana P. Spasić Igor G. Panjković Milana D. Vučković Biljana A. |
| author_sort | Mitić Gorana P. |
| collection | DOAJ |
| description | Introduction: Women with coronavirus disease 2019 (COVID-19) during pregnancy are more likely to develop a severe form of the disease and have unfavorable pregnancy outcomes. Case report: We report the case of a 21-year-old woman diagnosed with disseminated intravascular coagulation (DIC) caused by COVID-19, and subsequent early neonatal death. She was referred to the hospital at 29 gestational weeks due to progression of COVID-19 symptoms. Increased plasma thrombin and fibrinolytic activity were observed on admission , and low molecular weight heparin and antibiotic therapy were started immediately. After fully developing laboratory DIC was diagnosed, an emergency Cesarean section was performed. Upon delivery severe perinatal asphyxia was diagnosed in a neonate, manifested as atony and cardiac arrest. Despite cardiopulmonary resuscitation, the newborn passed away three hours after birth. The mother recovered in several days, she was discharged in good clinical condition. Conclusion: The presented clinical case indicates the importance of an early diagnosis of DIC in SARS-CoV-2-positive pregnant women, timely therapeutic decisions, psychological support, and long-term follow-up of physical and psychological conditions. |
| format | Article |
| id | doaj-art-575a9e04f95f45098073a1fe1e7b6153 |
| institution | Kabale University |
| issn | 2334-9492 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Srpsko lekarsko drustvo |
| record_format | Article |
| series | Hospital Pharmacology |
| spelling | doaj-art-575a9e04f95f45098073a1fe1e7b61532025-02-05T13:12:34ZengSrpsko lekarsko drustvoHospital Pharmacology2334-94922024-01-011131469147510.5937/hpimj2403469M2334-94922403469MA case report of an early neonatal death accompanied by disseminated intravascular coagulation caused by severe acute respiratory syndrome Coronavirus-2 infectionMitić Gorana P.0https://orcid.org/0000-0002-8041-4144Spasić Igor G.1Panjković Milana D.2https://orcid.org/0000-0002-9427-2992Vučković Biljana A.3University of Novi Sad, Faculty of Medicine, Department of Pathophysiology and Laboratory Medicine, Novi Sad, SerbiaHealth Care Institution for Laboratory Diagnostics Medlab, Novi Sad, SerbiaUniversity of Novi Sad, Faculty of Medicine, Department of Pathophysiology and Laboratory Medicine, Novi Sad, SerbiaUniversity of Novi Sad, Faculty of Medicine, Department of Pathophysiology and Laboratory Medicine, Novi Sad, SerbiaIntroduction: Women with coronavirus disease 2019 (COVID-19) during pregnancy are more likely to develop a severe form of the disease and have unfavorable pregnancy outcomes. Case report: We report the case of a 21-year-old woman diagnosed with disseminated intravascular coagulation (DIC) caused by COVID-19, and subsequent early neonatal death. She was referred to the hospital at 29 gestational weeks due to progression of COVID-19 symptoms. Increased plasma thrombin and fibrinolytic activity were observed on admission , and low molecular weight heparin and antibiotic therapy were started immediately. After fully developing laboratory DIC was diagnosed, an emergency Cesarean section was performed. Upon delivery severe perinatal asphyxia was diagnosed in a neonate, manifested as atony and cardiac arrest. Despite cardiopulmonary resuscitation, the newborn passed away three hours after birth. The mother recovered in several days, she was discharged in good clinical condition. Conclusion: The presented clinical case indicates the importance of an early diagnosis of DIC in SARS-CoV-2-positive pregnant women, timely therapeutic decisions, psychological support, and long-term follow-up of physical and psychological conditions.https://scindeks-clanci.ceon.rs/data/pdf/2334-9492/2024/2334-94922403469M.pdfcovid-19disseminated intravascular coagulationearly neonatal deathpregnancysars-cov-2 |
| spellingShingle | Mitić Gorana P. Spasić Igor G. Panjković Milana D. Vučković Biljana A. A case report of an early neonatal death accompanied by disseminated intravascular coagulation caused by severe acute respiratory syndrome Coronavirus-2 infection Hospital Pharmacology covid-19 disseminated intravascular coagulation early neonatal death pregnancy sars-cov-2 |
| title | A case report of an early neonatal death accompanied by disseminated intravascular coagulation caused by severe acute respiratory syndrome Coronavirus-2 infection |
| title_full | A case report of an early neonatal death accompanied by disseminated intravascular coagulation caused by severe acute respiratory syndrome Coronavirus-2 infection |
| title_fullStr | A case report of an early neonatal death accompanied by disseminated intravascular coagulation caused by severe acute respiratory syndrome Coronavirus-2 infection |
| title_full_unstemmed | A case report of an early neonatal death accompanied by disseminated intravascular coagulation caused by severe acute respiratory syndrome Coronavirus-2 infection |
| title_short | A case report of an early neonatal death accompanied by disseminated intravascular coagulation caused by severe acute respiratory syndrome Coronavirus-2 infection |
| title_sort | case report of an early neonatal death accompanied by disseminated intravascular coagulation caused by severe acute respiratory syndrome coronavirus 2 infection |
| topic | covid-19 disseminated intravascular coagulation early neonatal death pregnancy sars-cov-2 |
| url | https://scindeks-clanci.ceon.rs/data/pdf/2334-9492/2024/2334-94922403469M.pdf |
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