PI3K/AKT/mTORC1 signalling pathway regulates MMP9 gene activation via transcription factor NF-κB in mammary epithelial cells of dairy cows

PI3K/AKT/mTORC1 signalling pathway regulates MMP9 gene activation via transcription factor NF-κB in mammary epithelial cells of dairy cows

Matrix metalloproteinase 9 (MMP9) plays a pivotal role in mammary ductal morphogenesis, angiogenesis and glandular tissue architecture remodeling. However, the molecular mechanism of MMP9 expression in mammary epithelial cells of dairy cows remains unclear. This study aimed to explore the underlying...

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Bibliographic Details
Main Authors: Yongjin Mao, Chen Su, Huilin Yang, Xiaocong Ma, Feng Zhao, Bo Qu, Yang Yang, Xiaoming Hou, Bing Zhao, Yingjun Cui
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Animal Biotechnology
Subjects:
Dairy cow
mammary epithelial cells
matrix metalloproteinase 9 (MMP9)
NF-κB
Online Access:https://www.tandfonline.com/doi/10.1080/10495398.2024.2314100
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