Rare Lung Diseases III: Pulmonary Langerhans’ Cell Histiocytosis
Pulmonary Langerhans’ cell histiocytosis (PLCH) is an unusual cystic lung disease that is also characterized by extrapulmonary manifestations. The current review discusses the presenting features and relevant diagnostic testing and treatment options for PLCH in the context of a clinical case. While...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2010-01-01
|
| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/2010/216240 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832546730845929472 |
|---|---|
| author | Stephen C Juvet David Hwang Gregory P Downey |
| author_facet | Stephen C Juvet David Hwang Gregory P Downey |
| author_sort | Stephen C Juvet |
| collection | DOAJ |
| description | Pulmonary Langerhans’ cell histiocytosis (PLCH) is an unusual cystic lung disease that is also characterized by extrapulmonary manifestations. The current review discusses the presenting features and relevant diagnostic testing and treatment options for PLCH in the context of a clinical case. While the focus of the present article is adult PLCH and its pulmonary manifestations, it is important for clinicians to distinguish the adult and pediatric forms of the disease, as well as to be alert for possible extrapulmonary complications. A major theme of the current series of articles on rare lung diseases has been the translation of insights gained from fundamental research to the clinic. Accordingly, the understanding of dendritic cell biology in this disease has led to important advances in the care of patients with PLCH. |
| format | Article |
| id | doaj-art-5745c68703c44666825af868f2719292 |
| institution | Kabale University |
| issn | 1198-2241 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj-art-5745c68703c44666825af868f27192922025-02-03T06:47:24ZengWileyCanadian Respiratory Journal1198-22412010-01-01173e55e6210.1155/2010/216240Rare Lung Diseases III: Pulmonary Langerhans’ Cell HistiocytosisStephen C Juvet0David Hwang1Gregory P Downey2Division of Respirology and Clinician-Scientist Training Program, Department of Medicine, University Health Network, Toronto, Ontario, CanadaDepartment of Laboratory Medicine and Pathobiology, and Toronto General Hospital/University Health Network, Toronto, Ontario, CanadaDepartments of Medicine, Pediatrics, and Immunology, National Jewish Health and University of Colorado, Aurora, Colorado, USAPulmonary Langerhans’ cell histiocytosis (PLCH) is an unusual cystic lung disease that is also characterized by extrapulmonary manifestations. The current review discusses the presenting features and relevant diagnostic testing and treatment options for PLCH in the context of a clinical case. While the focus of the present article is adult PLCH and its pulmonary manifestations, it is important for clinicians to distinguish the adult and pediatric forms of the disease, as well as to be alert for possible extrapulmonary complications. A major theme of the current series of articles on rare lung diseases has been the translation of insights gained from fundamental research to the clinic. Accordingly, the understanding of dendritic cell biology in this disease has led to important advances in the care of patients with PLCH.http://dx.doi.org/10.1155/2010/216240 |
| spellingShingle | Stephen C Juvet David Hwang Gregory P Downey Rare Lung Diseases III: Pulmonary Langerhans’ Cell Histiocytosis Canadian Respiratory Journal |
| title | Rare Lung Diseases III: Pulmonary Langerhans’ Cell Histiocytosis |
| title_full | Rare Lung Diseases III: Pulmonary Langerhans’ Cell Histiocytosis |
| title_fullStr | Rare Lung Diseases III: Pulmonary Langerhans’ Cell Histiocytosis |
| title_full_unstemmed | Rare Lung Diseases III: Pulmonary Langerhans’ Cell Histiocytosis |
| title_short | Rare Lung Diseases III: Pulmonary Langerhans’ Cell Histiocytosis |
| title_sort | rare lung diseases iii pulmonary langerhans cell histiocytosis |
| url | http://dx.doi.org/10.1155/2010/216240 |
| work_keys_str_mv | AT stephencjuvet rarelungdiseasesiiipulmonarylangerhanscellhistiocytosis AT davidhwang rarelungdiseasesiiipulmonarylangerhanscellhistiocytosis AT gregorypdowney rarelungdiseasesiiipulmonarylangerhanscellhistiocytosis |