Catalytic Enantioselective Synthesis of Axially Chiral Diaryl Ethers Via Asymmetric Povarov Reaction Enabled Desymmetrization

Abstract Axially chiral diaryl ethers represent a distinct class of atropisomers, characterized by a unique dual C─O axes system, which have been found in a variety of natural products, pharmaceuticals, and ligands. However, the catalytic enantioselective synthesis of these atropoisomers poses signi...

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Bibliographic Details
Main Authors: Zidan Ye, Wansen Xie, Wei Liu, Changyu Zhou, Xiaoyu Yang
Format: Article
Language:English
Published: Wiley 2024-09-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202403125
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