Is Chronic Inflammation a Possible Cause of Obesity-Related Depression?
Adult obesity has been associated with depression, especially in women. Whether depression leads to obesity or obesity causes depression is unclear. Chronic inflammation is observed in obesity and depression. In 63 obese women without additional diseases depression level was assessed with the Beck&#...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2009-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2009/439107 |
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| _version_ | 1832550789823856640 |
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| author | Magdalena Olszanecka-Glinianowicz Barbara Zahorska-Markiewicz Piotr Kocełak Joanna Janowska Elżbieta Semik-Grabarczyk Tomasz Wikarek Wojciech Gruszka Piotr Dąbrowski |
| author_facet | Magdalena Olszanecka-Glinianowicz Barbara Zahorska-Markiewicz Piotr Kocełak Joanna Janowska Elżbieta Semik-Grabarczyk Tomasz Wikarek Wojciech Gruszka Piotr Dąbrowski |
| author_sort | Magdalena Olszanecka-Glinianowicz |
| collection | DOAJ |
| description | Adult obesity has been associated with depression, especially in women. Whether depression leads to obesity or obesity causes depression is unclear. Chronic inflammation is observed in obesity and depression. In 63 obese women without additional diseases depression level was assessed with the Beck's questionnaire. After evaluation of depression level study group was divided into groups according to the mood status (A—without depression, B—mild depression, and C—severe depression), and serum concentration of TNF-α, sTNFs, leptin, and IL-6 were measured by ELISA. No differences in age, body mass, BMI, and body composition were observed in study groups. We did not observe differences of serum concentrations of TNF-α, sTNFRs, leptin, and IL-6 between subgroup A and subgroups B and C. It seems that circulating adipokines did not exert influence on depression levels in obese women. |
| format | Article |
| id | doaj-art-5737d3a194e94ba996f666b12004723f |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-5737d3a194e94ba996f666b12004723f2025-02-03T06:05:50ZengWileyMediators of Inflammation0962-93511466-18612009-01-01200910.1155/2009/439107439107Is Chronic Inflammation a Possible Cause of Obesity-Related Depression?Magdalena Olszanecka-Glinianowicz0Barbara Zahorska-Markiewicz1Piotr Kocełak2Joanna Janowska3Elżbieta Semik-Grabarczyk4Tomasz Wikarek5Wojciech Gruszka6Piotr Dąbrowski7Department of Pathophysiology, Medical University of Silesia, 40-752 Katowice, PolandDepartment of Pathophysiology, Medical University of Silesia, 40-752 Katowice, PolandDepartment of Pathophysiology, Medical University of Silesia, 40-752 Katowice, PolandDepartment of Pathophysiology, Medical University of Silesia, 40-752 Katowice, PolandDepartment of Pathophysiology, Medical University of Silesia, 40-752 Katowice, PolandDepartment of Pathophysiology, Medical University of Silesia, 40-752 Katowice, PolandDepartment of Pathophysiology, Medical University of Silesia, 40-752 Katowice, PolandDepartment of Pathophysiology, Medical University of Silesia, 40-752 Katowice, PolandAdult obesity has been associated with depression, especially in women. Whether depression leads to obesity or obesity causes depression is unclear. Chronic inflammation is observed in obesity and depression. In 63 obese women without additional diseases depression level was assessed with the Beck's questionnaire. After evaluation of depression level study group was divided into groups according to the mood status (A—without depression, B—mild depression, and C—severe depression), and serum concentration of TNF-α, sTNFs, leptin, and IL-6 were measured by ELISA. No differences in age, body mass, BMI, and body composition were observed in study groups. We did not observe differences of serum concentrations of TNF-α, sTNFRs, leptin, and IL-6 between subgroup A and subgroups B and C. It seems that circulating adipokines did not exert influence on depression levels in obese women.http://dx.doi.org/10.1155/2009/439107 |
| spellingShingle | Magdalena Olszanecka-Glinianowicz Barbara Zahorska-Markiewicz Piotr Kocełak Joanna Janowska Elżbieta Semik-Grabarczyk Tomasz Wikarek Wojciech Gruszka Piotr Dąbrowski Is Chronic Inflammation a Possible Cause of Obesity-Related Depression? Mediators of Inflammation |
| title | Is Chronic Inflammation a Possible Cause of Obesity-Related Depression? |
| title_full | Is Chronic Inflammation a Possible Cause of Obesity-Related Depression? |
| title_fullStr | Is Chronic Inflammation a Possible Cause of Obesity-Related Depression? |
| title_full_unstemmed | Is Chronic Inflammation a Possible Cause of Obesity-Related Depression? |
| title_short | Is Chronic Inflammation a Possible Cause of Obesity-Related Depression? |
| title_sort | is chronic inflammation a possible cause of obesity related depression |
| url | http://dx.doi.org/10.1155/2009/439107 |
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