A Meta-analysis of the Effect of Probiotic <i>Lactobacillus</i> sp. as Immunomodulating Inflammatory Responses
Lactobacillus sp. is considered an indispensable probiotic, and this probiotic has an effective role in maintaining the immune system. We evaluated the effect of the probiotic Lactobacillus sp. on modulating inflammation in several cases. In collecting the literature, we used databases from the Web...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2024-06-01
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| Series: | Medeniyet Medical Journal |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-53822 |
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| _version_ | 1832582746169409536 |
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| author | Waode Fifin ERVINA Sri Pantja MADYAWATI Iswinarno Doso SAPUTRO Dodi SAFARI Rury Eryna PUTRI Salma ZULQAIDA |
| author_facet | Waode Fifin ERVINA Sri Pantja MADYAWATI Iswinarno Doso SAPUTRO Dodi SAFARI Rury Eryna PUTRI Salma ZULQAIDA |
| author_sort | Waode Fifin ERVINA |
| collection | DOAJ |
| description | Lactobacillus sp. is considered an indispensable probiotic, and this probiotic has an effective role in maintaining the immune system. We evaluated the effect of the probiotic Lactobacillus sp. on modulating inflammation in several cases. In collecting the literature, we used databases from the Web of Science, the Cochrane Central Register of Controlled Trials, PubMed, and Embase. Studies that met the inclusion criteria were analyzed using Review Manager (version 5.4). A p-value of <0.05 of the total effect is considered statistically significant. Finally, 1895 references were retrieved and 20 were included in the meta-analysis. This meta-analysis suggested that most cases in this study were healthy elderly who received treatment with Lactobacillus sp. Lactobacillus sp. has a positive effect on B cells, eosinophils, IgE, NK cells, TNF-α, and IL-10. Lactobacillus could regulate the immune system by modulating inflammation in the healthy elderly. |
| format | Article |
| id | doaj-art-57279b65f93c431e855527ccb50d9aed |
| institution | Kabale University |
| issn | 2149-2042 2149-4606 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Medeniyet Medical Journal |
| spelling | doaj-art-57279b65f93c431e855527ccb50d9aed2025-01-29T10:24:23ZengGalenos Publishing HouseMedeniyet Medical Journal2149-20422149-46062024-06-0139212213110.4274/MMJ.galenos.2024.53822MEDJ-53822A Meta-analysis of the Effect of Probiotic <i>Lactobacillus</i> sp. as Immunomodulating Inflammatory ResponsesWaode Fifin ERVINA0Sri Pantja MADYAWATI1Iswinarno Doso SAPUTRO2Dodi SAFARI3Rury Eryna PUTRI4Salma ZULQAIDA5Postgraduate School of Universitas Airlangga, Master of Immunology Program, Surabaya, IndonesiaPost Graduate School of Universitas Airlangga, Surabaya, IndonesiaSoetomo General Academic Hospital, Surabaya, IndonesiaNational Research and Innovation Agency, Cibinong, IndonesiaPostgraduate School of Universitas Airlangga, Master of Forensic Program, Surabaya, IndonesiaPostgraduate School of Universitas Airlangga, Master of Immunology Program, Surabaya, IndonesiaLactobacillus sp. is considered an indispensable probiotic, and this probiotic has an effective role in maintaining the immune system. We evaluated the effect of the probiotic Lactobacillus sp. on modulating inflammation in several cases. In collecting the literature, we used databases from the Web of Science, the Cochrane Central Register of Controlled Trials, PubMed, and Embase. Studies that met the inclusion criteria were analyzed using Review Manager (version 5.4). A p-value of <0.05 of the total effect is considered statistically significant. Finally, 1895 references were retrieved and 20 were included in the meta-analysis. This meta-analysis suggested that most cases in this study were healthy elderly who received treatment with Lactobacillus sp. Lactobacillus sp. has a positive effect on B cells, eosinophils, IgE, NK cells, TNF-α, and IL-10. Lactobacillus could regulate the immune system by modulating inflammation in the healthy elderly.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-53822good health and well-beinginflammation responseimmune systemlactobacillus sp. |
| spellingShingle | Waode Fifin ERVINA Sri Pantja MADYAWATI Iswinarno Doso SAPUTRO Dodi SAFARI Rury Eryna PUTRI Salma ZULQAIDA A Meta-analysis of the Effect of Probiotic <i>Lactobacillus</i> sp. as Immunomodulating Inflammatory Responses Medeniyet Medical Journal good health and well-being inflammation response immune system lactobacillus sp. |
| title | A Meta-analysis of the Effect of Probiotic <i>Lactobacillus</i> sp. as Immunomodulating Inflammatory Responses |
| title_full | A Meta-analysis of the Effect of Probiotic <i>Lactobacillus</i> sp. as Immunomodulating Inflammatory Responses |
| title_fullStr | A Meta-analysis of the Effect of Probiotic <i>Lactobacillus</i> sp. as Immunomodulating Inflammatory Responses |
| title_full_unstemmed | A Meta-analysis of the Effect of Probiotic <i>Lactobacillus</i> sp. as Immunomodulating Inflammatory Responses |
| title_short | A Meta-analysis of the Effect of Probiotic <i>Lactobacillus</i> sp. as Immunomodulating Inflammatory Responses |
| title_sort | meta analysis of the effect of probiotic i lactobacillus i sp as immunomodulating inflammatory responses |
| topic | good health and well-being inflammation response immune system lactobacillus sp. |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-53822 |
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