Electrical Impedance Dermography: Background, Current State, and Emerging Clinical Opportunities

Electrical impedance dermography (EID), based on electrical impedance spectroscopy, is a specific technique for the evaluation of skin disorders that relies upon the application and measurement of painless, alternating electrical current. EID assesses pathological changes to the normal composition a...

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Main Authors: Elise K. Brunsgaard, Benjamin Sanchez, Douglas Grossman
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Dermatology Research and Practice
Online Access:http://dx.doi.org/10.1155/2024/2085098
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author Elise K. Brunsgaard
Benjamin Sanchez
Douglas Grossman
author_facet Elise K. Brunsgaard
Benjamin Sanchez
Douglas Grossman
author_sort Elise K. Brunsgaard
collection DOAJ
description Electrical impedance dermography (EID), based on electrical impedance spectroscopy, is a specific technique for the evaluation of skin disorders that relies upon the application and measurement of painless, alternating electrical current. EID assesses pathological changes to the normal composition and architecture of the skin that influence the flow of electrical current, including changes associated with inflammation, keratinocyte and melanocyte carcinogenesis, and scarring. Assessing the electrical properties of the skin across a range of frequencies and in multiple directions of current flow can provide diagnostic information to aid in the identification of pathologic skin conditions. EID holds the promise of serving as a diagnostic biomarker and potential to be used in skin cancer detection and staging. EID may also be useful as a biomarker in monitoring effectiveness of treatment in individual patients and in therapeutic research. This review highlights ongoing efforts to improve mechanistic understanding of skin electrical changes, study of EID in a variety of clinical contexts, and further refine the technology to find greater clinical use in dermatology and dermatologic research.
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spelling doaj-art-571b74dc0b4b43f3b24a941e0eb8064f2025-02-03T11:26:00ZengWileyDermatology Research and Practice1687-61132024-01-01202410.1155/2024/2085098Electrical Impedance Dermography: Background, Current State, and Emerging Clinical OpportunitiesElise K. Brunsgaard0Benjamin Sanchez1Douglas Grossman2Huntsman Cancer InstituteDepartment of Electrical and Computer EngineeringHuntsman Cancer InstituteElectrical impedance dermography (EID), based on electrical impedance spectroscopy, is a specific technique for the evaluation of skin disorders that relies upon the application and measurement of painless, alternating electrical current. EID assesses pathological changes to the normal composition and architecture of the skin that influence the flow of electrical current, including changes associated with inflammation, keratinocyte and melanocyte carcinogenesis, and scarring. Assessing the electrical properties of the skin across a range of frequencies and in multiple directions of current flow can provide diagnostic information to aid in the identification of pathologic skin conditions. EID holds the promise of serving as a diagnostic biomarker and potential to be used in skin cancer detection and staging. EID may also be useful as a biomarker in monitoring effectiveness of treatment in individual patients and in therapeutic research. This review highlights ongoing efforts to improve mechanistic understanding of skin electrical changes, study of EID in a variety of clinical contexts, and further refine the technology to find greater clinical use in dermatology and dermatologic research.http://dx.doi.org/10.1155/2024/2085098
spellingShingle Elise K. Brunsgaard
Benjamin Sanchez
Douglas Grossman
Electrical Impedance Dermography: Background, Current State, and Emerging Clinical Opportunities
Dermatology Research and Practice
title Electrical Impedance Dermography: Background, Current State, and Emerging Clinical Opportunities
title_full Electrical Impedance Dermography: Background, Current State, and Emerging Clinical Opportunities
title_fullStr Electrical Impedance Dermography: Background, Current State, and Emerging Clinical Opportunities
title_full_unstemmed Electrical Impedance Dermography: Background, Current State, and Emerging Clinical Opportunities
title_short Electrical Impedance Dermography: Background, Current State, and Emerging Clinical Opportunities
title_sort electrical impedance dermography background current state and emerging clinical opportunities
url http://dx.doi.org/10.1155/2024/2085098
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AT benjaminsanchez electricalimpedancedermographybackgroundcurrentstateandemergingclinicalopportunities
AT douglasgrossman electricalimpedancedermographybackgroundcurrentstateandemergingclinicalopportunities