Burden of Sickle Cell Disease in Ghana: The Korle-Bu Experience

In Africa, sickle cell disease (SCD) is a major public health problem with over 200,000 babies born per year. In Ghana, approximately 15,000 (2%) of Ghanaian newborns are diagnosed with SCD annually. A retrospective review of medical records of all SCD patients aged 13 years and above, who presented...

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Main Authors: Eugenia V. Asare, Ivor Wilson, Amma A. Benneh-Akwasi Kuma, Yvonne Dei-Adomakoh, Fredericka Sey, Edeghonghon Olayemi
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Advances in Hematology
Online Access:http://dx.doi.org/10.1155/2018/6161270
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author Eugenia V. Asare
Ivor Wilson
Amma A. Benneh-Akwasi Kuma
Yvonne Dei-Adomakoh
Fredericka Sey
Edeghonghon Olayemi
author_facet Eugenia V. Asare
Ivor Wilson
Amma A. Benneh-Akwasi Kuma
Yvonne Dei-Adomakoh
Fredericka Sey
Edeghonghon Olayemi
author_sort Eugenia V. Asare
collection DOAJ
description In Africa, sickle cell disease (SCD) is a major public health problem with over 200,000 babies born per year. In Ghana, approximately 15,000 (2%) of Ghanaian newborns are diagnosed with SCD annually. A retrospective review of medical records of all SCD patients aged 13 years and above, who presented to the sickle cell clinic at Ghana Institute of Clinical Genetics (GICG), Korle-Bu, from 1st January 2013 to 31st December 2014, was carried out, using a data abstraction instrument to document their phenotypes, demographics, attendance/clinic visits, pattern of attendance, and common complications seen. During the period under review 5,451 patients were seen at the GICG, with 20,788 clinic visits. The phenotypes were HbSS (55.7%) and HbSC (39.6%) with other sickle cell phenotypes (4.7%). Out of the 20,788 clinic visits, outpatient visits were 15,802 (76%), and urgent care visits were 4,986 (24%), out of which 128 (2.6%) patients were admitted to the Teaching Hospital for further management of their acute complications. There were 904 patient referrals (out of 5,451 patients) for specialist care; the 3 specialties that had the most referrals were Obstetrics and Gynaecology (168 patients), Orthopaedics (150 patients), and Ophthalmology (143 patients). In 2014, complications seen at KBTH included 53 patients with avascular necrosis (AVN) and 61 patients with chronic leg ulcers. Our centre has a large number of patients living with sickle cell disease. From our experience, early recognition and referral of sickle cell related complications can reduce morbidity and mortality associated with this disease. A multidisciplinary approach to care of SCD patients is therefore important.
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spelling doaj-art-56b5a73503014fdf85fa6c9897a5c90c2025-02-03T05:45:50ZengWileyAdvances in Hematology1687-91041687-91122018-01-01201810.1155/2018/61612706161270Burden of Sickle Cell Disease in Ghana: The Korle-Bu ExperienceEugenia V. Asare0Ivor Wilson1Amma A. Benneh-Akwasi Kuma2Yvonne Dei-Adomakoh3Fredericka Sey4Edeghonghon Olayemi5Ghana Institute of Clinical Genetics, Korle-Bu, Accra, GhanaGhana Institute of Clinical Genetics, Korle-Bu, Accra, GhanaDepartment of Haematology, College of Health Sciences, University of Ghana, Accra, GhanaGhana Institute of Clinical Genetics, Korle-Bu, Accra, GhanaGhana Institute of Clinical Genetics, Korle-Bu, Accra, GhanaGhana Institute of Clinical Genetics, Korle-Bu, Accra, GhanaIn Africa, sickle cell disease (SCD) is a major public health problem with over 200,000 babies born per year. In Ghana, approximately 15,000 (2%) of Ghanaian newborns are diagnosed with SCD annually. A retrospective review of medical records of all SCD patients aged 13 years and above, who presented to the sickle cell clinic at Ghana Institute of Clinical Genetics (GICG), Korle-Bu, from 1st January 2013 to 31st December 2014, was carried out, using a data abstraction instrument to document their phenotypes, demographics, attendance/clinic visits, pattern of attendance, and common complications seen. During the period under review 5,451 patients were seen at the GICG, with 20,788 clinic visits. The phenotypes were HbSS (55.7%) and HbSC (39.6%) with other sickle cell phenotypes (4.7%). Out of the 20,788 clinic visits, outpatient visits were 15,802 (76%), and urgent care visits were 4,986 (24%), out of which 128 (2.6%) patients were admitted to the Teaching Hospital for further management of their acute complications. There were 904 patient referrals (out of 5,451 patients) for specialist care; the 3 specialties that had the most referrals were Obstetrics and Gynaecology (168 patients), Orthopaedics (150 patients), and Ophthalmology (143 patients). In 2014, complications seen at KBTH included 53 patients with avascular necrosis (AVN) and 61 patients with chronic leg ulcers. Our centre has a large number of patients living with sickle cell disease. From our experience, early recognition and referral of sickle cell related complications can reduce morbidity and mortality associated with this disease. A multidisciplinary approach to care of SCD patients is therefore important.http://dx.doi.org/10.1155/2018/6161270
spellingShingle Eugenia V. Asare
Ivor Wilson
Amma A. Benneh-Akwasi Kuma
Yvonne Dei-Adomakoh
Fredericka Sey
Edeghonghon Olayemi
Burden of Sickle Cell Disease in Ghana: The Korle-Bu Experience
Advances in Hematology
title Burden of Sickle Cell Disease in Ghana: The Korle-Bu Experience
title_full Burden of Sickle Cell Disease in Ghana: The Korle-Bu Experience
title_fullStr Burden of Sickle Cell Disease in Ghana: The Korle-Bu Experience
title_full_unstemmed Burden of Sickle Cell Disease in Ghana: The Korle-Bu Experience
title_short Burden of Sickle Cell Disease in Ghana: The Korle-Bu Experience
title_sort burden of sickle cell disease in ghana the korle bu experience
url http://dx.doi.org/10.1155/2018/6161270
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