Ankle edema after administration of selective serotonin reuptake inhibitors
Clinical manifestations of drug-induced skin reactions include a wide range of symptoms, from mild drug-induced exanthemas to dangerous and life-threatening generalized systematic reactions. Druginduced skin reactions to psychotropic medication are usually associated with antiepileptic drugs. Howeve...
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| Format: | Article |
| Language: | English |
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Wiley
2018-06-01
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| Series: | Mental Illness |
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| Online Access: | https://www.pagepress.org/journals/index.php/mi/article/view/7364 |
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| author | Konstantinos Kontoangelos Marina Ecomomou Charalambos Papageorgiou |
| author_facet | Konstantinos Kontoangelos Marina Ecomomou Charalambos Papageorgiou |
| author_sort | Konstantinos Kontoangelos |
| collection | DOAJ |
| description | Clinical manifestations of drug-induced skin reactions include a wide range of symptoms, from mild drug-induced exanthemas to dangerous and life-threatening generalized systematic reactions. Druginduced skin reactions to psychotropic medication are usually associated with antiepileptic drugs. However, a significant role can be assigned to selective serotonin reuptake inhibitors. We report a case of a female patient, who after approximately one month therapy with escitalopram developed a bilateral ankle edema, which resolved completely within the first week following its discontinuation. Although serious complications are rare, clinicians should be aware of severe skin complications in patients treated with antidepressants, which necessitate careful clinical monitoring and management. Individualization of pharmacotherapy is crucial, together with regular evaluation of safety and tolerance of the treatment. |
| format | Article |
| id | doaj-art-56b4764cea1645d8a138b4832c56c91f |
| institution | Kabale University |
| issn | 2036-7457 2036-7465 |
| language | English |
| publishDate | 2018-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mental Illness |
| spelling | doaj-art-56b4764cea1645d8a138b4832c56c91f2025-02-03T06:05:57ZengWileyMental Illness2036-74572036-74652018-06-0110110.4081/mi.2018.73643944Ankle edema after administration of selective serotonin reuptake inhibitorsKonstantinos Kontoangelos0Marina Ecomomou1Charalambos Papageorgiou2First Department of Psychiatry, Eginition Hospital, Athens; University Mental Health Research Institute, AthensFirst Department of Psychiatry, Eginition Hospital, Athens; University Mental Health Research Institute, AthensFirst Department of Psychiatry, Eginition Hospital, Athens; University Mental Health Research Institute, AthensClinical manifestations of drug-induced skin reactions include a wide range of symptoms, from mild drug-induced exanthemas to dangerous and life-threatening generalized systematic reactions. Druginduced skin reactions to psychotropic medication are usually associated with antiepileptic drugs. However, a significant role can be assigned to selective serotonin reuptake inhibitors. We report a case of a female patient, who after approximately one month therapy with escitalopram developed a bilateral ankle edema, which resolved completely within the first week following its discontinuation. Although serious complications are rare, clinicians should be aware of severe skin complications in patients treated with antidepressants, which necessitate careful clinical monitoring and management. Individualization of pharmacotherapy is crucial, together with regular evaluation of safety and tolerance of the treatment.https://www.pagepress.org/journals/index.php/mi/article/view/7364escitalopram,oedema, depression, serotonin,skin, cutaneous effects |
| spellingShingle | Konstantinos Kontoangelos Marina Ecomomou Charalambos Papageorgiou Ankle edema after administration of selective serotonin reuptake inhibitors Mental Illness escitalopram,oedema, depression, serotonin,skin, cutaneous effects |
| title | Ankle edema after administration of selective serotonin reuptake inhibitors |
| title_full | Ankle edema after administration of selective serotonin reuptake inhibitors |
| title_fullStr | Ankle edema after administration of selective serotonin reuptake inhibitors |
| title_full_unstemmed | Ankle edema after administration of selective serotonin reuptake inhibitors |
| title_short | Ankle edema after administration of selective serotonin reuptake inhibitors |
| title_sort | ankle edema after administration of selective serotonin reuptake inhibitors |
| topic | escitalopram,oedema, depression, serotonin,skin, cutaneous effects |
| url | https://www.pagepress.org/journals/index.php/mi/article/view/7364 |
| work_keys_str_mv | AT konstantinoskontoangelos ankleedemaafteradministrationofselectiveserotoninreuptakeinhibitors AT marinaecomomou ankleedemaafteradministrationofselectiveserotoninreuptakeinhibitors AT charalambospapageorgiou ankleedemaafteradministrationofselectiveserotoninreuptakeinhibitors |