Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic Applications
Skin wounds and compromised wound healing are major concerns for the public. Although skin wound healing has been studied for decades, the molecular and cellular mechanisms behind the process are still not completely clear. The systemic responses to trauma involve the body’s inflammatory and immunom...
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Format: | Article |
Language: | English |
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Wiley
2022-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2022/5344085 |
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author | Yara Adib Armand Bensussan Laurence Michel |
author_facet | Yara Adib Armand Bensussan Laurence Michel |
author_sort | Yara Adib |
collection | DOAJ |
description | Skin wounds and compromised wound healing are major concerns for the public. Although skin wound healing has been studied for decades, the molecular and cellular mechanisms behind the process are still not completely clear. The systemic responses to trauma involve the body’s inflammatory and immunomodulatory cellular and humoral networks. Studies over the years provided essential insights into a complex and dynamic immunity during the cutaneous wound healing process. This review will focus on innate cell populations involved in the initial phase of this orchestrated process, including innate cells from both the skin and the immune system. |
format | Article |
id | doaj-art-56a21d7a48cb48b89223bbdd92ebc787 |
institution | Kabale University |
issn | 1466-1861 |
language | English |
publishDate | 2022-01-01 |
publisher | Wiley |
record_format | Article |
series | Mediators of Inflammation |
spelling | doaj-art-56a21d7a48cb48b89223bbdd92ebc7872025-02-03T05:50:31ZengWileyMediators of Inflammation1466-18612022-01-01202210.1155/2022/5344085Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic ApplicationsYara Adib0Armand Bensussan1Laurence Michel2INSERM U976INSERM U976INSERM U976Skin wounds and compromised wound healing are major concerns for the public. Although skin wound healing has been studied for decades, the molecular and cellular mechanisms behind the process are still not completely clear. The systemic responses to trauma involve the body’s inflammatory and immunomodulatory cellular and humoral networks. Studies over the years provided essential insights into a complex and dynamic immunity during the cutaneous wound healing process. This review will focus on innate cell populations involved in the initial phase of this orchestrated process, including innate cells from both the skin and the immune system.http://dx.doi.org/10.1155/2022/5344085 |
spellingShingle | Yara Adib Armand Bensussan Laurence Michel Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic Applications Mediators of Inflammation |
title | Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic Applications |
title_full | Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic Applications |
title_fullStr | Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic Applications |
title_full_unstemmed | Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic Applications |
title_short | Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic Applications |
title_sort | cutaneous wound healing a review about innate immune response and current therapeutic applications |
url | http://dx.doi.org/10.1155/2022/5344085 |
work_keys_str_mv | AT yaraadib cutaneouswoundhealingareviewaboutinnateimmuneresponseandcurrenttherapeuticapplications AT armandbensussan cutaneouswoundhealingareviewaboutinnateimmuneresponseandcurrenttherapeuticapplications AT laurencemichel cutaneouswoundhealingareviewaboutinnateimmuneresponseandcurrenttherapeuticapplications |