Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic Applications

Skin wounds and compromised wound healing are major concerns for the public. Although skin wound healing has been studied for decades, the molecular and cellular mechanisms behind the process are still not completely clear. The systemic responses to trauma involve the body’s inflammatory and immunom...

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Main Authors: Yara Adib, Armand Bensussan, Laurence Michel
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2022/5344085
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author Yara Adib
Armand Bensussan
Laurence Michel
author_facet Yara Adib
Armand Bensussan
Laurence Michel
author_sort Yara Adib
collection DOAJ
description Skin wounds and compromised wound healing are major concerns for the public. Although skin wound healing has been studied for decades, the molecular and cellular mechanisms behind the process are still not completely clear. The systemic responses to trauma involve the body’s inflammatory and immunomodulatory cellular and humoral networks. Studies over the years provided essential insights into a complex and dynamic immunity during the cutaneous wound healing process. This review will focus on innate cell populations involved in the initial phase of this orchestrated process, including innate cells from both the skin and the immune system.
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series Mediators of Inflammation
spelling doaj-art-56a21d7a48cb48b89223bbdd92ebc7872025-02-03T05:50:31ZengWileyMediators of Inflammation1466-18612022-01-01202210.1155/2022/5344085Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic ApplicationsYara Adib0Armand Bensussan1Laurence Michel2INSERM U976INSERM U976INSERM U976Skin wounds and compromised wound healing are major concerns for the public. Although skin wound healing has been studied for decades, the molecular and cellular mechanisms behind the process are still not completely clear. The systemic responses to trauma involve the body’s inflammatory and immunomodulatory cellular and humoral networks. Studies over the years provided essential insights into a complex and dynamic immunity during the cutaneous wound healing process. This review will focus on innate cell populations involved in the initial phase of this orchestrated process, including innate cells from both the skin and the immune system.http://dx.doi.org/10.1155/2022/5344085
spellingShingle Yara Adib
Armand Bensussan
Laurence Michel
Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic Applications
Mediators of Inflammation
title Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic Applications
title_full Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic Applications
title_fullStr Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic Applications
title_full_unstemmed Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic Applications
title_short Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic Applications
title_sort cutaneous wound healing a review about innate immune response and current therapeutic applications
url http://dx.doi.org/10.1155/2022/5344085
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