Advances in Meniscal Tissue Engineering

Meniscal tears are the most common knee injuries and have a poor ability of healing. In the last few decades, several techniques have been increasingly used to optimize meniscal healing. Current research efforts of tissue engineering try to combine cell-based therapy, growth factors, gene therapy, a...

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Main Authors: Umile Giuseppe Longo, Mattia Loppini, Francisco Forriol, Giovanni Romeo, Nicola Maffulli, Vincenzo Denaro
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2012/420346
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author Umile Giuseppe Longo
Mattia Loppini
Francisco Forriol
Giovanni Romeo
Nicola Maffulli
Vincenzo Denaro
author_facet Umile Giuseppe Longo
Mattia Loppini
Francisco Forriol
Giovanni Romeo
Nicola Maffulli
Vincenzo Denaro
author_sort Umile Giuseppe Longo
collection DOAJ
description Meniscal tears are the most common knee injuries and have a poor ability of healing. In the last few decades, several techniques have been increasingly used to optimize meniscal healing. Current research efforts of tissue engineering try to combine cell-based therapy, growth factors, gene therapy, and reabsorbable scaffolds to promote healing of meniscal defects. Preliminary studies did not allow to draw definitive conclusions on the use of these techniques for routine management of meniscal lesions. We performed a review of the available literature on current techniques of tissue engineering for the management of meniscal tears.
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series Stem Cells International
spelling doaj-art-568dc1fe291e44edae21a417d80abad02025-02-03T05:52:21ZengWileyStem Cells International1687-966X1687-96782012-01-01201210.1155/2012/420346420346Advances in Meniscal Tissue EngineeringUmile Giuseppe Longo0Mattia Loppini1Francisco Forriol2Giovanni Romeo3Nicola Maffulli4Vincenzo Denaro5Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University of Rome, Via Álvaro del Portillo 200, 00128 Rome, ItalyDepartment of Orthopaedic and Trauma Surgery, Campus Bio-Medico University of Rome, Via Álvaro del Portillo 200, 00128 Rome, ItalyUniversity CEU San Pablo, 28003 Madrid, SpainDepartment of Orthopaedic and Trauma Surgery, Campus Bio-Medico University of Rome, Via Álvaro del Portillo 200, 00128 Rome, ItalyCentre for Sports and Exercise Medicine, Barts and The London School of Medicine and Dentistry, Mile End Hospital, 275 Bancroft Road, London E1 4DG, UKDepartment of Orthopaedic and Trauma Surgery, Campus Bio-Medico University of Rome, Via Álvaro del Portillo 200, 00128 Rome, ItalyMeniscal tears are the most common knee injuries and have a poor ability of healing. In the last few decades, several techniques have been increasingly used to optimize meniscal healing. Current research efforts of tissue engineering try to combine cell-based therapy, growth factors, gene therapy, and reabsorbable scaffolds to promote healing of meniscal defects. Preliminary studies did not allow to draw definitive conclusions on the use of these techniques for routine management of meniscal lesions. We performed a review of the available literature on current techniques of tissue engineering for the management of meniscal tears.http://dx.doi.org/10.1155/2012/420346
spellingShingle Umile Giuseppe Longo
Mattia Loppini
Francisco Forriol
Giovanni Romeo
Nicola Maffulli
Vincenzo Denaro
Advances in Meniscal Tissue Engineering
Stem Cells International
title Advances in Meniscal Tissue Engineering
title_full Advances in Meniscal Tissue Engineering
title_fullStr Advances in Meniscal Tissue Engineering
title_full_unstemmed Advances in Meniscal Tissue Engineering
title_short Advances in Meniscal Tissue Engineering
title_sort advances in meniscal tissue engineering
url http://dx.doi.org/10.1155/2012/420346
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