Advances in Meniscal Tissue Engineering
Meniscal tears are the most common knee injuries and have a poor ability of healing. In the last few decades, several techniques have been increasingly used to optimize meniscal healing. Current research efforts of tissue engineering try to combine cell-based therapy, growth factors, gene therapy, a...
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Format: | Article |
Language: | English |
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Wiley
2012-01-01
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Series: | Stem Cells International |
Online Access: | http://dx.doi.org/10.1155/2012/420346 |
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author | Umile Giuseppe Longo Mattia Loppini Francisco Forriol Giovanni Romeo Nicola Maffulli Vincenzo Denaro |
author_facet | Umile Giuseppe Longo Mattia Loppini Francisco Forriol Giovanni Romeo Nicola Maffulli Vincenzo Denaro |
author_sort | Umile Giuseppe Longo |
collection | DOAJ |
description | Meniscal tears are the most common knee injuries and have a poor ability of healing. In the last few decades, several techniques have been increasingly used to optimize meniscal healing. Current research efforts of tissue engineering try to combine cell-based therapy, growth factors, gene therapy, and reabsorbable scaffolds to promote healing of meniscal defects. Preliminary studies did not allow to draw definitive conclusions on the use of these techniques for routine management of meniscal lesions. We performed a review of the available literature on current techniques of tissue engineering for the management of meniscal tears. |
format | Article |
id | doaj-art-568dc1fe291e44edae21a417d80abad0 |
institution | Kabale University |
issn | 1687-966X 1687-9678 |
language | English |
publishDate | 2012-01-01 |
publisher | Wiley |
record_format | Article |
series | Stem Cells International |
spelling | doaj-art-568dc1fe291e44edae21a417d80abad02025-02-03T05:52:21ZengWileyStem Cells International1687-966X1687-96782012-01-01201210.1155/2012/420346420346Advances in Meniscal Tissue EngineeringUmile Giuseppe Longo0Mattia Loppini1Francisco Forriol2Giovanni Romeo3Nicola Maffulli4Vincenzo Denaro5Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University of Rome, Via Álvaro del Portillo 200, 00128 Rome, ItalyDepartment of Orthopaedic and Trauma Surgery, Campus Bio-Medico University of Rome, Via Álvaro del Portillo 200, 00128 Rome, ItalyUniversity CEU San Pablo, 28003 Madrid, SpainDepartment of Orthopaedic and Trauma Surgery, Campus Bio-Medico University of Rome, Via Álvaro del Portillo 200, 00128 Rome, ItalyCentre for Sports and Exercise Medicine, Barts and The London School of Medicine and Dentistry, Mile End Hospital, 275 Bancroft Road, London E1 4DG, UKDepartment of Orthopaedic and Trauma Surgery, Campus Bio-Medico University of Rome, Via Álvaro del Portillo 200, 00128 Rome, ItalyMeniscal tears are the most common knee injuries and have a poor ability of healing. In the last few decades, several techniques have been increasingly used to optimize meniscal healing. Current research efforts of tissue engineering try to combine cell-based therapy, growth factors, gene therapy, and reabsorbable scaffolds to promote healing of meniscal defects. Preliminary studies did not allow to draw definitive conclusions on the use of these techniques for routine management of meniscal lesions. We performed a review of the available literature on current techniques of tissue engineering for the management of meniscal tears.http://dx.doi.org/10.1155/2012/420346 |
spellingShingle | Umile Giuseppe Longo Mattia Loppini Francisco Forriol Giovanni Romeo Nicola Maffulli Vincenzo Denaro Advances in Meniscal Tissue Engineering Stem Cells International |
title | Advances in Meniscal Tissue Engineering |
title_full | Advances in Meniscal Tissue Engineering |
title_fullStr | Advances in Meniscal Tissue Engineering |
title_full_unstemmed | Advances in Meniscal Tissue Engineering |
title_short | Advances in Meniscal Tissue Engineering |
title_sort | advances in meniscal tissue engineering |
url | http://dx.doi.org/10.1155/2012/420346 |
work_keys_str_mv | AT umilegiuseppelongo advancesinmeniscaltissueengineering AT mattialoppini advancesinmeniscaltissueengineering AT franciscoforriol advancesinmeniscaltissueengineering AT giovanniromeo advancesinmeniscaltissueengineering AT nicolamaffulli advancesinmeniscaltissueengineering AT vincenzodenaro advancesinmeniscaltissueengineering |