Evaluation of the Early Development of 6-Month-Old Babies in the Case of Maternal Postpartum Depression with or Without Bipolar Disorder
Background: The first year of life is the period of greatest brain plasticity. Postpartum depression can adversely affect the first interactions with the child and, consequently, their emotional, social, and cognitive development. Objectives: First, to describe the developmental profile of six-month...
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MDPI AG
2024-12-01
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| Series: | Children |
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| author | Jokthan Guivarch Mélanie-Lou Persia Laure Le Treut Pauline Grandgeorge Federico Solla Hugo Pergeline Michel Dugnat Florence Askenazy François Poinso Arthur Varoquaux Arnaud Fernandez |
| author_facet | Jokthan Guivarch Mélanie-Lou Persia Laure Le Treut Pauline Grandgeorge Federico Solla Hugo Pergeline Michel Dugnat Florence Askenazy François Poinso Arthur Varoquaux Arnaud Fernandez |
| author_sort | Jokthan Guivarch |
| collection | DOAJ |
| description | Background: The first year of life is the period of greatest brain plasticity. Postpartum depression can adversely affect the first interactions with the child and, consequently, their emotional, social, and cognitive development. Objectives: First, to describe the developmental profile of six-month-old infants of mothers suffering from severe postpartum depression, and, second, to compare the development of infants whose mothers suffer from depression with or without bipolar disorder. Methods: This is a retrospective descriptive study on 6-month-old babies hospitalized with their mothers at the Marseille Mother–Baby Unit (MBU) for maternal postpartum depression with or without bipolar disorder. Mothers were clinically diagnosed by a psychiatrist specialized in postpartum depression using the DSM-5; infant development was assessed at 6 months by an independent health professional using the revised Brunet–Lézine Scale, which allowed the calculation of global and partial developmental quotients (DQ). Results: We followed 40 mother–infant dyads. None of the 40 infants had a global developmental delay. However, maternal depression was significantly associated with poorer sociability (mean sociability DQ score of 94 ± 9.6, <i>p</i> < 0.001) and lower postural development (mean postural DQ score of 96.2 ± 8.9 *, <i>p</i> < 0.001) in the infants at 6 months of age. Postural development was significantly lower in children of bipolar mothers than in children of non-bipolar mothers (<i>p</i> = 0.03). Conclusions: Postpartum depression was associated with a weakness in sociability and posture at the age of 6 months, without relevant developmental delay. Screening infants at an early age with specific tools allows for earlier intervention, which would positively influence their developmental trajectory. |
| format | Article |
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| institution | Kabale University |
| issn | 2227-9067 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj-art-5672e90e87e64be3b5f38dc36a59dabe2025-01-24T13:26:59ZengMDPI AGChildren2227-90672024-12-011211110.3390/children12010011Evaluation of the Early Development of 6-Month-Old Babies in the Case of Maternal Postpartum Depression with or Without Bipolar DisorderJokthan Guivarch0Mélanie-Lou Persia1Laure Le Treut2Pauline Grandgeorge3Federico Solla4Hugo Pergeline5Michel Dugnat6Florence Askenazy7François Poinso8Arthur Varoquaux9Arnaud Fernandez10Faculty of Medicine, Aix-Marseille University, 13385 Marseille, FranceDepartment of Child Psychiatry, Assistance Publique Hôpitaux de Marseille (APHM), 13009 Marseille, FranceDepartment of Child Psychiatry, Valvert Hospital, 13011 Marseille, FranceDepartment of Child Psychiatry, Assistance Publique Hôpitaux de Marseille (APHM), 13009 Marseille, FrancePediatric Surgery Department, Lenval University Children’s Hospital, 57 Bd Californie, 06200 Nice, FranceFaculty of Medicine, Aix-Marseille University, 13385 Marseille, FranceDepartment of Child Psychiatry, Assistance Publique Hôpitaux de Marseille (APHM), 13009 Marseille, FranceLenval University Children’s Hospital, SUPEA (University Department of Child and Adolescent Psychiatry), Competence Center for Rare Diseases with Psychiatric Expression (CC MREP), Expert Center for Pediatric Psychotrauma (CE2P), 06200 Nice, FranceFaculty of Medicine, Aix-Marseille University, 13385 Marseille, FranceFaculty of Medicine, Aix-Marseille University, 13385 Marseille, FranceLenval University Children’s Hospital, SUPEA (University Department of Child and Adolescent Psychiatry), Competence Center for Rare Diseases with Psychiatric Expression (CC MREP), Expert Center for Pediatric Psychotrauma (CE2P), 06200 Nice, FranceBackground: The first year of life is the period of greatest brain plasticity. Postpartum depression can adversely affect the first interactions with the child and, consequently, their emotional, social, and cognitive development. Objectives: First, to describe the developmental profile of six-month-old infants of mothers suffering from severe postpartum depression, and, second, to compare the development of infants whose mothers suffer from depression with or without bipolar disorder. Methods: This is a retrospective descriptive study on 6-month-old babies hospitalized with their mothers at the Marseille Mother–Baby Unit (MBU) for maternal postpartum depression with or without bipolar disorder. Mothers were clinically diagnosed by a psychiatrist specialized in postpartum depression using the DSM-5; infant development was assessed at 6 months by an independent health professional using the revised Brunet–Lézine Scale, which allowed the calculation of global and partial developmental quotients (DQ). Results: We followed 40 mother–infant dyads. None of the 40 infants had a global developmental delay. However, maternal depression was significantly associated with poorer sociability (mean sociability DQ score of 94 ± 9.6, <i>p</i> < 0.001) and lower postural development (mean postural DQ score of 96.2 ± 8.9 *, <i>p</i> < 0.001) in the infants at 6 months of age. Postural development was significantly lower in children of bipolar mothers than in children of non-bipolar mothers (<i>p</i> = 0.03). Conclusions: Postpartum depression was associated with a weakness in sociability and posture at the age of 6 months, without relevant developmental delay. Screening infants at an early age with specific tools allows for earlier intervention, which would positively influence their developmental trajectory.https://www.mdpi.com/2227-9067/12/1/11postpartum depressionchild developmentdevelopment quotientsmother–baby unitBrunet–Lézine scalemother–infant interaction |
| spellingShingle | Jokthan Guivarch Mélanie-Lou Persia Laure Le Treut Pauline Grandgeorge Federico Solla Hugo Pergeline Michel Dugnat Florence Askenazy François Poinso Arthur Varoquaux Arnaud Fernandez Evaluation of the Early Development of 6-Month-Old Babies in the Case of Maternal Postpartum Depression with or Without Bipolar Disorder Children postpartum depression child development development quotients mother–baby unit Brunet–Lézine scale mother–infant interaction |
| title | Evaluation of the Early Development of 6-Month-Old Babies in the Case of Maternal Postpartum Depression with or Without Bipolar Disorder |
| title_full | Evaluation of the Early Development of 6-Month-Old Babies in the Case of Maternal Postpartum Depression with or Without Bipolar Disorder |
| title_fullStr | Evaluation of the Early Development of 6-Month-Old Babies in the Case of Maternal Postpartum Depression with or Without Bipolar Disorder |
| title_full_unstemmed | Evaluation of the Early Development of 6-Month-Old Babies in the Case of Maternal Postpartum Depression with or Without Bipolar Disorder |
| title_short | Evaluation of the Early Development of 6-Month-Old Babies in the Case of Maternal Postpartum Depression with or Without Bipolar Disorder |
| title_sort | evaluation of the early development of 6 month old babies in the case of maternal postpartum depression with or without bipolar disorder |
| topic | postpartum depression child development development quotients mother–baby unit Brunet–Lézine scale mother–infant interaction |
| url | https://www.mdpi.com/2227-9067/12/1/11 |
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